中医药多元证据整合方法学MERGE框架

赖鸿皓; 王浙; 李滢; 唐文静; 王蓓蓓; 孙培栋; 孙铭谣; 黄嘉杰; 肖志攀; 李颖; 赵晨; 商洪才; 杨克虎; 刘杰; 葛龙

doi:10.12290/xhyxzz.2023-0083

中医药多元证据整合方法学MERGE框架

doi: 10.12290/xhyxzz.2023-0083

赖鸿皓^{1, 2},
王浙³,
李滢²,
唐文静²,
王蓓蓓²,
孙培栋²,
孙铭谣³,
黄嘉杰⁴,
肖志攀⁵,
李颖^{1, 2},
赵晨⁶,
商洪才⁷,
杨克虎^{8, 9, 10},
刘杰^{11, 12, ,},
葛龙^{1, 2, 9, 10, ,}

1.
兰州大学公共卫生学院循证社会科学研究中心，兰州 730000
2.
兰州大学公共卫生学院社会医学与卫生事业管理研究所，兰州 730000
3.
兰州大学护理学院循证护理研究中心，兰州 730000
4.
甘肃中医药大学护理学院，兰州 730030
5.
甘肃中医药大学中西医结合学院，兰州 730030
6.
中国中医科学院中医临床基础医学研究所，北京 100700
7.
北京中医药大学东直门医院中医内科学教育部和北京市重点实验室，北京 100700
8.
兰州大学基础医学院循证医学中心，兰州 730000
9.
甘肃省循证中医药协同创新基地，兰州 730000
10.
甘肃省循证医学与临床转化重点实验室，兰州 730000
11.
中国中医科学院广安门医院肿瘤科，北京 100053
12.
中国中医药循证医学中心，北京 100700

基金项目:

国家自然科学基金 82204931

中国中医科学院科技创新工程 CI2021A05502

详细信息

通讯作者:
刘杰, E-mail: dr.liujie@163.com

葛龙, E-mail: gelong2009@163.com

赖鸿皓、王浙对本文同等贡献

中图分类号: R181.2; R21
计量
- 文章访问数: 280
- HTML全文浏览量: 39
- PDF下载量: 57
- 被引次数: 0
出版历程
- 收稿日期: 2023-02-15
- 录用日期: 2023-03-22
- 网络出版日期: 2023-04-18
- 刊出日期: 2024-01-30

Multi-evidence Integration Methodology for Traditional Chinese Medicine: the MERGE Framework

LAI Honghao^{1, 2},
WANG Zhe³,
LI Ying²,
TANG Wenjing²,
WANG Beibei²,
SUN Peidong²,
SUN Mingyao³,
HUANG Jiajie⁴,
XIAO Zhipan⁵,
LI Ying^{1, 2},
ZHAO Chen⁶,
SHANG Hongcai⁷,
YANG Kehu^{8, 9, 10},
LIU Jie^{11, 12
, ,},
GE Long^{1, 2, 9, 10
, ,}

1.
Evidence-based Social Science Research Center, School of Public Health, Lanzhou University, Lanzhou 730000, China
2.
Department of Social Science and Health Management, School of Public Health, Lanzhou University, Lanzhou 730000, China
3.
Evidence-based Nursing Center, School of Nursing, Lanzhou University, Lanzhou 730000, China
4.
College of Nursing, Gansu University of Chinese Medicine, Lanzhou 730030, China
5.
School of Traditional Chinese and Western Medicine, Gansu University of Chinese Medicine, Lanzhou 730030, China
6.
Institute of Basic Research In Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China
7.
Key Laboratory of Chinese Internal Medicine of Ministry of Education, Beijing Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China
8.
Evidence-based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou 730000, China
9.
Collaborative Innovation Center for Evidence-based Traditional Chinese Medicine in Gansu Province, Lanzhou 730000, China
10.
Key Laboratory of Evidence-based Medicine and Knowledge Translation of Gansu Province, Lanzhou 730000, China
11.
Department of Oncology, Guang'anmen Hospital, Chinese Academy of Traditional Chinese Medicine, Beijing 100053, China
12.
China Center for Evidence-based Traditional Chinese Medicine, Beijing 100700, China

Funds:

National Natural Science Foundation of China 82204931

China Academy of Chinese Medical Sciences Innovation Fund CI2021A05502

More Information

Corresponding author: LIU Jie, E-mail: dr.liujie@163.com; GE Long, E-mail: gelong2009@163.com

摘要

摘要: 在循证医学时代下, 依托规范的技术方法和标准化的操作规程发掘中医药独特优势, 是实现中医药现代化、国际化发展并惠泽人类的必由之路。中医理论、人用经验和研究证据三结合证据体系的提出标志着中医药特色评价体系思维方法取得了重要进步, 经过恰当方法整合后的多元证据体是中医药临床指南推荐意见和循证卫生决策的有力支撑。本文基于当前国际证据合成与分级方法学前沿进展, 初步提出中医药多元证据整合的方法学框架——MERGE(Merge Evidence-based Research and artificial intelliGence to support smart dEcision)框架, 以期为中医药循证医学方法学体系的完善和发展提供借鉴和参考。
- 循证医学 /
- 中医药 /
- 多元证据 /
- 证据整合 /
- MERGE框架
Abstract: In the era of evidence-based medicine, it is necessary to explore the unique advantages of traditional Chinese medicine (TCM) based on standardized technical methods and operating procedures in order to achieve the modernization and internationalization of TCM and benefit all humanity. The proposal of a three-pronged evidence system combining TCM theory, human experience and experimental evidence marks an important progress in the thinking method of the TCM evaluation system. The multi-evidence body integrated through appropriate methods provides a strong support for the clinical guideline recommendations and evidence-based health decision-making in TCM. Based on the current methodological progress of international evidence synthesis and grading, this paper proposes a novel approach for integrating multi-evidence in TCM: the MERGE framework. The aim is to establish a solid foundation for the development of this methodology and provide guidance for the advancement of evidence-based medicine framework in TCM.
- evidence-based medicine /
- traditional Chinese medicine /
- multi-evidence /
- evidence integration /
- MERGE framework
注释:

作者贡献：赖鸿皓、王浙负责搜集、整理资料和撰写论文初稿；葛龙、赖鸿皓、王浙、李滢、唐文静、王蓓蓓、孙培栋、孙铭谣、黄嘉杰、肖志攀、李颖负责构思及讨论框架内容、结构和方法流程；葛龙、赖鸿皓、孙铭谣、黄嘉杰、李颖负责构建和优化框架；赵晨、商洪才、杨克虎、刘杰负责修订论文初稿；葛龙负责结构设计、组建团队及修订论文。

利益冲突：所有作者均声明不存在利益冲突

HTML全文

图 1 中医药领域整合研究证据的方法学框架——MERGE

RCT(randomized controlled trials): 随机对照试验；Scoping Reivew: 范围综述；RWS(real world study): 真实世界研究

Figure 1. Methodological framework for integrating evidence in TCM—MERGE

下载: 全尺寸图片幻灯片

图 2 多元证据(研究证据、中医理论和人用经验)整合的方法学框架

Figure 2. Methodological framework for multivariate evidence integration

下载: 全尺寸图片幻灯片

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中医药多元证据整合方法学MERGE框架

doi: 10.12290/xhyxzz.2023-0083

通讯作者:
刘杰, E-mail: dr.liujie@163.com

葛龙, E-mail: gelong2009@163.com

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Multi-evidence Integration Methodology for Traditional Chinese Medicine: the MERGE Framework

Corresponding author: LIU Jie, E-mail: dr.liujie@163.com; GE Long, E-mail: gelong2009@163.com

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中医药多元证据整合方法学MERGE框架

doi: 10.12290/xhyxzz.2023-0083

通讯作者: 刘杰, E-mail: dr.liujie@163.com 葛龙, E-mail: gelong2009@163.com

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Multi-evidence Integration Methodology for Traditional Chinese Medicine: the MERGE Framework

Corresponding author: LIU Jie, E-mail: dr.liujie@163.com; GE Long, E-mail: gelong2009@163.com

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通讯作者:
刘杰, E-mail: dr.liujie@163.com

葛龙, E-mail: gelong2009@163.com