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中医药多元证据整合方法学MERGE框架

赖鸿皓 王浙 李滢 唐文静 王蓓蓓 孙培栋 孙铭谣 黄嘉杰 肖志攀 李颖 赵晨 商洪才 杨克虎 刘杰 葛龙

赖鸿皓, 王浙, 李滢, 唐文静, 王蓓蓓, 孙培栋, 孙铭谣, 黄嘉杰, 肖志攀, 李颖, 赵晨, 商洪才, 杨克虎, 刘杰, 葛龙. 中医药多元证据整合方法学MERGE框架[J]. 协和医学杂志, 2024, 15(1): 172-182. doi: 10.12290/xhyxzz.2023-0083
引用本文: 赖鸿皓, 王浙, 李滢, 唐文静, 王蓓蓓, 孙培栋, 孙铭谣, 黄嘉杰, 肖志攀, 李颖, 赵晨, 商洪才, 杨克虎, 刘杰, 葛龙. 中医药多元证据整合方法学MERGE框架[J]. 协和医学杂志, 2024, 15(1): 172-182. doi: 10.12290/xhyxzz.2023-0083
LAI Honghao, WANG Zhe, LI Ying, TANG Wenjing, WANG Beibei, SUN Peidong, SUN Mingyao, HUANG Jiajie, XIAO Zhipan, LI Ying, ZHAO Chen, SHANG Hongcai, YANG Kehu, LIU Jie, GE Long. Multi-evidence Integration Methodology for Traditional Chinese Medicine: the MERGE Framework[J]. Medical Journal of Peking Union Medical College Hospital, 2024, 15(1): 172-182. doi: 10.12290/xhyxzz.2023-0083
Citation: LAI Honghao, WANG Zhe, LI Ying, TANG Wenjing, WANG Beibei, SUN Peidong, SUN Mingyao, HUANG Jiajie, XIAO Zhipan, LI Ying, ZHAO Chen, SHANG Hongcai, YANG Kehu, LIU Jie, GE Long. Multi-evidence Integration Methodology for Traditional Chinese Medicine: the MERGE Framework[J]. Medical Journal of Peking Union Medical College Hospital, 2024, 15(1): 172-182. doi: 10.12290/xhyxzz.2023-0083

中医药多元证据整合方法学MERGE框架

doi: 10.12290/xhyxzz.2023-0083
基金项目: 

国家自然科学基金 82204931

中国中医科学院科技创新工程 CI2021A05502

详细信息
    通讯作者:

    刘杰, E-mail: dr.liujie@163.com

    葛龙, E-mail: gelong2009@163.com

    赖鸿皓、王浙对本文同等贡献

    赖鸿皓、王浙对本文同等贡献

  • 中图分类号: R181.2; R21

Multi-evidence Integration Methodology for Traditional Chinese Medicine: the MERGE Framework

Funds: 

National Natural Science Foundation of China 82204931

China Academy of Chinese Medical Sciences Innovation Fund CI2021A05502

More Information
  • 摘要: 在循证医学时代下, 依托规范的技术方法和标准化的操作规程发掘中医药独特优势, 是实现中医药现代化、国际化发展并惠泽人类的必由之路。中医理论、人用经验和研究证据三结合证据体系的提出标志着中医药特色评价体系思维方法取得了重要进步, 经过恰当方法整合后的多元证据体是中医药临床指南推荐意见和循证卫生决策的有力支撑。本文基于当前国际证据合成与分级方法学前沿进展, 初步提出中医药多元证据整合的方法学框架——MERGE(Merge Evidence-based Research and artificial intelliGence to support smart dEcision)框架, 以期为中医药循证医学方法学体系的完善和发展提供借鉴和参考。
    作者贡献:赖鸿皓、王浙负责搜集、整理资料和撰写论文初稿;葛龙、赖鸿皓、王浙、李滢、唐文静、王蓓蓓、孙培栋、孙铭谣、黄嘉杰、肖志攀、李颖负责构思及讨论框架内容、结构和方法流程;葛龙、赖鸿皓、孙铭谣、黄嘉杰、李颖负责构建和优化框架;赵晨、商洪才、杨克虎、刘杰负责修订论文初稿;葛龙负责结构设计、组建团队及修订论文。
    利益冲突:所有作者均声明不存在利益冲突
  • 图  1  中医药领域整合研究证据的方法学框架——MERGE

    RCT(randomized controlled trials): 随机对照试验;Scoping Reivew: 范围综述;RWS(real world study): 真实世界研究

    Figure  1.  Methodological framework for integrating evidence in TCM—MERGE

    图  2  多元证据(研究证据、中医理论和人用经验)整合的方法学框架

    Figure  2.  Methodological framework for multivariate evidence integration

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出版历程
  • 收稿日期:  2023-02-15
  • 录用日期:  2023-03-22
  • 网络出版日期:  2023-04-18
  • 刊出日期:  2024-01-30

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