在线自适应放疗技术治疗局部进展期宫颈癌一例

王光宇; 晏俊芳; 汪之群; 张宇; 孙显松; 李晶; 李文博; 杨波; 张福泉

doi:10.12290/xhyxzz.2023-0076

在线自适应放疗技术治疗局部进展期宫颈癌一例

Locally Advanced Cervical Cancer Treated with Online Adaptive Radiotherapy: A Case Report

摘要

摘要: 在线自适应放疗技术是继调强放疗技术后的革命性进步，目前国内首个基于迭代锥形束CT(iterative cone beam computed tomography，iCBCT)的人工智能在线自适应放疗平台在北京协和医院被应用于临床治疗。本文报道北京协和医院放射治疗科首次采用基于iCBCT的在线自适应放疗技术治疗局部进展期宫颈癌患者1例，治疗后患者症状达到临床完全缓解且仅发生1级下消化道不良反应(腹泻)，未出现1级及以上的血液学、泌尿生殖系统及其他放疗相关不良反应。本文就该患者的临床诊疗过程及随访展开讨论，以期为后续大规模应用该技术提供临床借鉴。

Abstract: Online adaptive radiotherapy(OART)is considered to be a revolutionary technology after intensity-modulated radiotherapy. The first Chinese OART platform based on iterative cone beam computed tomography (iCBCT)has been applied in clinical treatment in Peking Union Medical College Hospital. This article reports the workflow and efficacy of first case with cervical cancer who received radical OART. After treatment, the patient achieved clinical complete remission with only a grade 1 radiation toxicity in the lower gastrointestinal tract. This article analyzes and discusses the clinical treatment process and follow-up data of this patient, aiming to provide clinical evidence for the subsequent large-scale application of artificial intelligence-driven iCBCT-guided OART technology.

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