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细菌性阴道炎实验室诊断研究进展

王喆 赵颖 徐英春

王喆, 赵颖, 徐英春. 细菌性阴道炎实验室诊断研究进展[J]. 协和医学杂志, 2023, 14(5): 1053-1059. doi: 10.12290/xhyxzz.2022-0677
引用本文: 王喆, 赵颖, 徐英春. 细菌性阴道炎实验室诊断研究进展[J]. 协和医学杂志, 2023, 14(5): 1053-1059. doi: 10.12290/xhyxzz.2022-0677
WANG Zhe, ZHAO Ying, XU Yingchun. Advances in Laboratory Diagnosis of Bacterial Vaginosis[J]. Medical Journal of Peking Union Medical College Hospital, 2023, 14(5): 1053-1059. doi: 10.12290/xhyxzz.2022-0677
Citation: WANG Zhe, ZHAO Ying, XU Yingchun. Advances in Laboratory Diagnosis of Bacterial Vaginosis[J]. Medical Journal of Peking Union Medical College Hospital, 2023, 14(5): 1053-1059. doi: 10.12290/xhyxzz.2022-0677

细菌性阴道炎实验室诊断研究进展

doi: 10.12290/xhyxzz.2022-0677
详细信息
    通讯作者:

    赵颖, E-mail: zhaoying28062806@163.com

  • 中图分类号: R711.31; S945.1+2; R446.5

Advances in Laboratory Diagnosis of Bacterial Vaginosis

More Information
  • 摘要: 细菌性阴道炎(bacterial vaginosis,BV)是由阴道内正常产生过氧化氢的乳杆菌减少、厌氧菌(动弯杆菌、普雷沃氏菌)和兼性厌氧菌(阴道加德纳菌、阴道阿托波菌)过度繁殖导致的阴道微生态平衡失调,表现为混合感染。BV不仅与盆腔炎、不孕症、性传播病原体(人乳头瘤病毒、人类免疫缺陷病毒、淋病奈瑟菌、沙眼衣原体等)感染风险增加相关,妊娠期合并BV还可能导致早期流产、早产、产后子宫内膜炎和新生儿低出生体重等不良妊娠结局。导致BV的病原体多样,且经治疗后复发率高。约10%~50%的BV患者无临床症状,易漏诊,而快速、准确的实验室检测能够对BV患者进行及时诊断和治疗、避免不良结局的发生。本文就BV的诊断标准、阴道微生态评价以及新型检测方法等研究进展作一综述,以期为BV的临床诊断和治疗提供借鉴和参考。
    作者贡献:王喆负责文献查阅、论文撰写;赵颖、徐英春负责论文审校。
    利益冲突:所有作者均声明不存在利益冲突
  • 表  1  Nugent评分标准

    评分 乳杆菌平均数量 加德纳菌及普雷沃氏菌平均数量 动弯杆菌平均数量
    0 4+ - -
    1 3+ 1+ 1+或2+
    2 2+ 2+ 3+或4+
    3 1+ 3+ -
    4 - 4+ -
    1+:平均细菌数量≥1个;2+:平均细菌数量为2~4个;3+:平均细菌数量为5~30个;4+:平均细菌数量>30个
    下载: 导出CSV
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  • 收稿日期:  2022-11-28
  • 录用日期:  2023-01-13
  • 刊出日期:  2023-09-30

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