Application of Near Infrared Spectroscopy in Cardiopulmonary Resuscitation
摘要: 随着社会的快节奏发展，心脏骤停已成为世界范围内的重大公共卫生问题。对于心脏骤停患者，心肺复苏的首要目标是保证大脑氧供，避免脑缺氧损伤。近年来，由于近红外光谱技术（near infrared spectroscopy，NIRS）可监测额叶皮质脑组织局部脑氧饱和度，实时反映脑氧供需平衡，其在心肺复苏领域中的应用受到广泛关注。NIRS技术可用于评估心肺复苏质量、早期发现再次骤停、判断患者的预后、评估脑血流自主调节水平、监测目标温度管理以及体外心肺复苏治疗患者的救治效果，具有较好的临床应用前景。本文主要就NIRS的原理及其在心肺复苏领域中的应用进展进行概述，以期指导临床实践。Abstract: With the rapid development of society, cardiac arrest has become a major public health problem worldwide. For cardiac arrest patients, the primary goal of CPR is to ensure oxygen supply to the brain and prevent brain hypoxia injury. Recently, near infrared spectroscopy (NIRS) and its application in cardiopulmonary resuscitation has attracted widespread attention because it can monitor local oxygen saturation of frontal cortex brain tissue, and reflect the balance of oxygen supply and demand in real time. NIRS technology can be used to evaluate the quality of cardiopulmonary resuscitation, detect repeat arrest early, predict prognosis of patients, evaluate the level of autonomous regulation of cerebral blood flow, as well as monitor target temperature management and the treatment effect of patients with extracorporeal cardiopulmonary resuscitation. Hence NIRS has good clinical application potential. This article mainly reviews the principle of NIRS and its application in cardiopulmonary resuscitation.
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