罕见病指南的制订：现状、挑战与机遇

周奇; 李沁原; 刘雅莉; 罗征秀; 张卫社; 陈彤; 李国保; 商洪才; 杨克虎; 张波; 陈耀龙; 张抒扬

doi:10.12290/xhyxzz.2022-0360

罕见病指南的制订：现状、挑战与机遇

doi: 10.12290/xhyxzz.2022-0360

周奇^{1, 2, 3},
李沁原⁴,
刘雅莉⁵,
罗征秀⁴,
张卫社⁶,
陈彤⁷,
李国保⁸,
商洪才⁹,
杨克虎¹,
张波¹⁰,
陈耀龙^{2, 3, ,},
张抒扬^{11, 12}

1.
兰州大学基础医学院循证医学中心，兰州 730000
2.
中国医学科学院循证评价与指南研究创新单元兰州大学基础医学院，兰州 730000
3.
中华医学会杂志社指南与标准研究中心，北京 100052
4.
国家儿童健康与疾病临床医学研究中心重庆医科大学附属儿童医院呼吸科儿童发育疾病研究教育部重点实验室儿科学重庆市重点实验室，重庆 401122
5.
国家儿童医学中心首都医科大学附属北京儿童医院临床流行病学与循证医学中心，北京 100045
6.
中南大学湘雅医院妇产科，长沙 410008
7.
复旦大学华山医院血液科，上海 200040
8.
国家感染性疾病临床医学研究中心深圳市第三人民医院肺病三科，深圳 518112
9.
北京中医药大学东直门医院中医内科学教育部和北京市重点实验室，北京 100700
10.
中国医学科学院北京协和医院药剂科，北京 100730
11.
中国医学科学院北京协和医院心内科，北京 100730
12.
中国医学科学院北京协和医院疑难重症及罕见病国家重点实验室，北京 100730

基金项目:

中央高校基本科研业务费专项资金资助 lzujbky-2021-ey13

详细信息

通讯作者:
陈耀龙, E-mail：chevidence@lzu.edu.cn

中图分类号: R181.2; R394
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- PDF下载量: 169
- 被引次数: 0
出版历程
- 收稿日期: 2022-06-28
- 录用日期: 2022-08-08
- 网络出版日期: 2022-08-22
- 刊出日期: 2023-05-30

The Development of Guidelines for Rare Diseases: Past, Present and Future

ZHOU Qi^{1, 2, 3},
LI Qinyuan⁴,
LIU Yali⁵,
LUO Zhengxiu⁴,
ZHANG Weishe⁶,
CHEN Tong⁷,
LI Guobao⁸,
SHANG Hongcai⁹,
YANG Kehu¹,
ZHANG Bo¹⁰,
CHEN Yaolong^{2, 3
, ,},
ZHANG Shuyang^{11, 12}

1.
Evidence-based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou 730000, China
2.
Research Unit of Evidence-based Evaluation and Guidelines, Chinese Academy of Medical Sciences, School of Basic Medical Sciences, Lanzhou University, Lanzhou 730000, China
3.
Guidelines and Standards Research Center of Chinese Medical Journals Publishing House, Beijing 100052, China
4.
Department of Respiratory, Medicine Children's Hospital of Chongqing Medical University, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, National Clinical Research Center for Child Health and Disorders, Chongqing 401122, China
5.
Center for Clinical Epidemiology and Evidence-based Medicine, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing 100045, China
6.
Department of Obstetrics and Gynecology, Xiangya Hospital Central South University, Changsha 410008, China
7.
Department of Hematology, Huashan Hospital, Fudan University, Shanghai 200040, China
8.
Department of Lung Disease, the Third People's Hospital of Shenzhen, National Clinical Research Center for Infectious Disease, Shenzhen 518112, China
9.
Key Laboratory of Chinese Internal Medicine of Ministry of Education, Beijing Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China
10.
Department of Pharmacy, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
11.
Department of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
12.
State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

Funds:

undamental Research Funds for the Central Universities lzujbky-2021-ey13

More Information

Corresponding author: CHEN Yaolong, E-mail: chevidence@lzu.edu.cn

摘要

摘要: 罕见病发病率虽然极低，但7000多种罕见病却影响着全球6%~8%的人群。罕见病临床实践指南作为改善罕见病患者健康结局的指导性文件发挥着越来越重要的作用。本文将系统阐述国内外罕见病指南的研究现状、面临的挑战以及当前的机遇，并在此基础上提出推动我国罕见病指南发展的思考与建议。
- 罕见病 /
- 临床实践指南 /
- 指南制订
Abstract: Although the incidence of rare diseases is extremely low, 6% to 8% of the global population are affected by more than 7000 rare diseases. Rare diseases guidelines are playing an increasingly important role as guiding documents in improving the health outcomes of patients with rare diseases. Therefore, we aim to systematically elaborate on the status quo, challenges and opportunities of rare disease guidelines at home and abroad, and put forward thoughts and suggestions on promoting the development of rare diseases guidelines in the future.
- rare diseases /
- clinical practice guideline /
- guideline development
注释:

作者贡献：周奇、李沁原负责数据提取、整理及论文初稿撰写；刘雅莉、罗征秀、张卫社、陈彤、李国保、商洪才、杨克虎、张波、张抒扬负责论文初稿修订；陈耀龙负责文章选题、结构设计、团队组建、数据核查及论文修订。

利益冲突：所有作者均声明不存在利益冲突

HTML全文

图 1 罕见病指南与国际及国内其他领域指南质量比较

注：采用AGREEⅡ工具对罕见病指南进行方法学质量评价，具体评价方法和数据来源详见参考文献[16-18]

下载: 全尺寸图片幻灯片

参考文献(59)

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留言板

罕见病指南的制订：现状、挑战与机遇

doi: 10.12290/xhyxzz.2022-0360

通讯作者:
陈耀龙, E-mail：chevidence@lzu.edu.cn

计量

The Development of Guidelines for Rare Diseases: Past, Present and Future

Corresponding author: CHEN Yaolong, E-mail: chevidence@lzu.edu.cn

计量

目录

留言板

罕见病指南的制订：现状、挑战与机遇

doi: 10.12290/xhyxzz.2022-0360

通讯作者: 陈耀龙, E-mail：chevidence@lzu.edu.cn

计量

出版历程

The Development of Guidelines for Rare Diseases: Past, Present and Future

Corresponding author: CHEN Yaolong, E-mail: chevidence@lzu.edu.cn

计量

出版历程

目录

通讯作者:
陈耀龙, E-mail：chevidence@lzu.edu.cn