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摘要: 克罗恩病(Crohn's disease,CD)属于炎症性肠病(inflammatory bowel disease,IBD)的一种,其发病率逐年升高,肠系膜脂肪包绕是CD的一种特殊征象,与CD肠道炎症和肠腔狭窄密切相关,是近年来研究的热点。肠系膜脂肪包绕的形成机制可能与脂肪细胞迁移和肠道微生物群易位相关。MRI、CT和超声是CD常用的影像学评估手段,可显示肠系膜脂肪包绕征象,并评估肠道炎症及肠腔狭窄。本文主要阐述肠系膜脂肪包绕的发病机制和临床意义,以及不同影像学方法的评价指标,并进一步探讨肠系膜脂肪包绕与CD炎症活动度和肠腔狭窄的关系,以期为临床提供参考。Abstract: Crohn's disease(CD)is a kind of inflammatory bowel disease, and its incidence rate is increasing year by year. Mesenteric creeping fat, a special sign of CD closely related to its intestinal inflammation and stenosis, has become a research hotspot in recent years. The formation mechanism of mesenteric creeping fat may be related to the migration of adipocytes and the translocation of intestinal microbiota. MRI, CT and US are commonly used imaging evaluation methods for CD, which can show the sign of creeping fat and evaluate the inflammation of intestinal wall and intestinal stenosis. However, the relationship between mesenteric creeping fat and inflammatory activity, stenosis and prognosis of CD needs to be further studied. The purpose of this review is to introduce the pathogenesis and clinical significance of mesenteric creeping fat, as well as the evaluation indicators of different imaging methods, and to further explore the relationship between mesenteric creeping fat and CD inflammatory activity and stenosis.
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Key words:
- inflammatory bowel disease /
- Crohn's disease /
- creeping fat /
- ultrasound
作者贡献:周梦园负责文献整理与论文撰写;朱庆莉负责论文修订及审校。利益冲突:所有作者均声明不存在利益冲突 -
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