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肠道菌群代谢产物在自身免疫性疾病中的作用

姜旭 杨华夏 张奉春

姜旭, 杨华夏, 张奉春. 肠道菌群代谢产物在自身免疫性疾病中的作用[J]. 协和医学杂志. doi: 10.12290/xhyxzz.2022-0246
引用本文: 姜旭, 杨华夏, 张奉春. 肠道菌群代谢产物在自身免疫性疾病中的作用[J]. 协和医学杂志. doi: 10.12290/xhyxzz.2022-0246
JIANG Xu, YANG Huaxia, ZHANG Fengchun. The Role of the Gut Microbial Metabolites in Autoimmune Diseases[J]. Medical Journal of Peking Union Medical College Hospital. doi: 10.12290/xhyxzz.2022-0246
Citation: JIANG Xu, YANG Huaxia, ZHANG Fengchun. The Role of the Gut Microbial Metabolites in Autoimmune Diseases[J]. Medical Journal of Peking Union Medical College Hospital. doi: 10.12290/xhyxzz.2022-0246

肠道菌群代谢产物在自身免疫性疾病中的作用

doi: 10.12290/xhyxzz.2022-0246
基金项目: 

国家自然科学基金(82171799);中国医学科学院医学与健康科技创新工程(2020-I2M-C&TB-011,2021-I2M-1-016)

详细信息
    通讯作者:

    杨华夏,E-mail:yanghuaxia2013@163.com

  • 中图分类号: R378;R593

The Role of the Gut Microbial Metabolites in Autoimmune Diseases

Funds: 

National Natural Science Foundation of China (82171799)

  • 摘要: 肠道菌群及其代谢产物在维持宿主免疫稳态方面具有重要作用,肠道菌群紊乱及代谢产物异常与多种自身免疫疾病的发生发展密切相关。肠道菌群代谢产物中,短链脂肪酸、色氨酸及衍生物、胆汁酸研究最为广泛,本文将重点阐述肠道菌群代谢产物的形成途径、对免疫应答的影响及与自身免疫性疾病的关联等,解析其在自身免疫疾病中的作用。
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出版历程
  • 收稿日期:  2022-05-02
  • 录用日期:  2022-07-15
  • 网络出版日期:  2022-07-29

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