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摘要: 随机对照试验(randomized controlled trial，RCT)是证实临床干预措施有效性的最佳研究手段。一项好的RCT应以具备临床意义和科学价值的主题为核心，重点关注干预及对照的设立、随机化方式及研究终点的选择。在实施过程中，把握伦理申请、研究注册、数据收集及研究定期审核等细节，从而保证研究的科学性及结果的可信度。Abstract: Randomized controlled trial(RCT) provides the most valid means of establishing the efficacy of clinical therapeutics. A good RCT should be based on topics with clinical significance and scientific value, and focus on the establishment of intervention and control, the method of randomization and the selection of primary endpoints. During the implementation process, details such as ethics application, research registration, data collection and regular review of the research are of great value to ensure the scientific validity of the trials and the credibility of the results.
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Key words:
- randomized controlled trial /
- intervention /
- randomization /
- primary endpoint
作者贡献：沈恺妮负责撰写论文；李剑负责审核及修订论文。利益冲突：所有作者均声明不存在利益冲突 -
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