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雌激素对呼吸道病毒感染的保护作用

陈筱涵 郁琦

陈筱涵, 郁琦. 雌激素对呼吸道病毒感染的保护作用[J]. 协和医学杂志, 2021, 12(2): 179-183. doi: 10.12290/xhyxzz.20200202
引用本文: 陈筱涵, 郁琦. 雌激素对呼吸道病毒感染的保护作用[J]. 协和医学杂志, 2021, 12(2): 179-183. doi: 10.12290/xhyxzz.20200202
CHEN Xiao-han, YU Qi. Protective Effect of Estrogen on Infection of Respiratory Virus[J]. Medical Journal of Peking Union Medical College Hospital, 2021, 12(2): 179-183. doi: 10.12290/xhyxzz.20200202
Citation: CHEN Xiao-han, YU Qi. Protective Effect of Estrogen on Infection of Respiratory Virus[J]. Medical Journal of Peking Union Medical College Hospital, 2021, 12(2): 179-183. doi: 10.12290/xhyxzz.20200202

雌激素对呼吸道病毒感染的保护作用

doi: 10.12290/xhyxzz.20200202
基金项目: 

国家重点研发计划 2018YFC1002105

详细信息
    通讯作者:

    郁琦  电话:010-69158621,E-mail:yuqimd@163.com

  • 中图分类号: R71; R18

Protective Effect of Estrogen on Infection of Respiratory Virus

Funds: 

National Key Research and Development Program 2018YFC1002105

More Information
    Corresponding author: YU Qi  Tel: 86-10-69158621, E-mail: yuqimd@163.com
  • 摘要: 雌激素是一种多功能甾体类激素,不仅对女性生殖系统,且对内分泌、心血管、代谢系统等均具有明显作用。雌激素对多种肺部疾病具有潜在治疗价值,雌激素受体信号转导在呼吸道病毒感染过程中,参与机体固有免疫、适应性免疫、组织修复过程。动物实验证实,雌激素可以降低炎性因子水平,抑制炎症反应,降低病毒滴度等,从而提高呼吸道病毒感染小鼠的存活率。本文探讨雌激素对于呼吸道病毒感染的保护作用及其机制。
    作者贡献:陈筱涵负责资料收集、论文撰写; 郁琦负责选题构思、论文修订。
    利益冲突:  无
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出版历程
  • 收稿日期:  2020-07-28
  • 录用日期:  2020-11-10
  • 网络出版日期:  2021-01-04
  • 刊出日期:  2021-05-30

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