Abstract: Patients with an uncorrectable single ventricle have a low survival rate. It is rare to see such patients of pregnancy, which has been reported with several cases. This univentricular patient of the second pregnancy with poorly generally condition has high mortality. Thanks to the cooperation of multidisciplinary team, the patient successfully underwent a cesarean section under general anesthesia. For providing some guidance to the clinical work, we will discuss our choice of anesthetic method and the management of general anesthesia on this patient.