急性脑静脉窦血栓是否需要血管内治疗?

Does Acute Cerebral Venous Sinus Thrombosis Require Endovascular Treatment?

  • 摘要: 脑静脉窦血栓较罕见, 发生率不足卒中的1%。其主要治疗方法是全身应用肝素抗凝, 但其中9%~13%的患者效果不佳。在病情快速恶化的患者中, 血管内治疗在技术上是可行的, 并在不同的病例系列分析和前瞻性队列研究中显示出良好的再通率。然而, 与单纯抗凝相比, 其能否改善血管内治疗亚组的临床结果仍不清楚。因此, 急性脑静脉窦血栓是否需要血管内治疗仍存在争议。

     

    Abstract: Cerebral venous sinus thrombosis(CVST) is rare and accounts for less than 1% of strokes. The mainstay treatment for CVST is systemic anticoagulation with heparin, but 9%-13% of patients have a poor outcome. In patients who show signs of rapid deterioration, endovascular treatment(ET) is technically feasible and has shown benefit with good recanalization rates in different case series and prospective cohorts. However, it remains unknown whether it improves the clinical outcome of the ET subgroup compared with anticoagulation alone. Therefore, whether acute CVST requires endovascular therapy remains controversial.

     

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