Abstract: Epilepsy is a common chronic disease of central nervous system with high disability rate and long duration, which is a medical and social public health problem urgently to be solved globally. In this context, the promotion of the clinical guidelines of epilepsy can help standardize the diagnosis and treatment of epilepsy, and to achieve the goal of controlling seizures and improving the prognosis of patients. At present, there is a large gap in the recognition of this disease in different countries and regions, and the uneven distribution of health resources is still quite common. There is still a lot of room for improvement of clinical guidelines of epilepsy. In this paper, we summarize the latest clinical guidelines of epilepsy and provide an outlook of its future.