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北京协和医院住院患者莫西沙星注射液利用分析

Use of Moxifloxacin Injection for Inpatients in Peking Union Medical College Hospital

    摘要
  • 摘要:
      目的  调查2010年全年和2011年第1季度莫西沙星注射液在本院的使用情况, 并对其中53例患者的应用进行回顾性分析。
      方法  通过北京协和医院信息系统获取2010年全年和2011年第1季度莫西沙星注射液使用数据, 查阅其中53例患者的病历, 记录用药目的、用药量、手术类型等相关数据并进行分析评价。
      结果  与2010年第1季度相比, 2011年第1季度莫西沙星注射液使用量同比增幅5.15%, 手术预防用药使用量同比增幅20.51%;患者个人用药总量逐渐增多(P=0.003), 18岁以下患者人数从2010年第1季度的2例增长至2011年第1季度的6例。53例患者中45例为手术患者, 其中39例(86.7%)将莫西沙星作为手术预防用药。21例具有感染病症患者的病原学送检率为52.38%(11例)。
      结论  莫西沙星注射液的应用较为广泛, 但部分应用存在不合理性, 尤其是手术预防用药, 应加强抗生素用药管理并对不合理用药进行干预。

     

    Abstract:
      Objective  To analyze the recent use of moxifloxacin injection in a tertiary hospital in Beijing.
      Methods  The use of moxifloxacin injection among inpatients in Peking Union Medical College Hospital in 2010 and the first quarter of 2011 was analyzed based on the hospital information system database. Meanwhile, the clinical records of 53 patients were reviewed for relevant data including medication purpose, dosage, and surgical procedures.
      Results  Compared to the first quarter of 2010, the total usage of moxifloxacin injection increased by 5.15% and the preoperative prophylaxis usage by 20.51% in the first quarter of 2011. The individual consumption also showed a growing tendency(P=0.003). With the number of patients younger than 18 years increased from 2 in the first quarter of 2010 to 6 in the first quarter of 2011. Of 45 patients who had preoperatively received moxifloxacin, 39 (86.7%) were for prophylaxis purpose. Of 21 patients with infectious diseases, etiological inspection was performed in 11 patients (52.38%).
      Conclusion  Moxifloxacin injection has been widely used in our hospital. However, its administration is not always rational, especially when applied for preoperative prophylaxis.

     

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