胰腺罕见病变的临床病理
Clinicopathological Features of Rare Pancreatic Lesions
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摘要:目的 总结11年来北京协和医院有病理诊断的胰腺罕见病变, 以提高对胰腺罕见病变的认识。方法 全面检索2000年至2011年北京协和医院病理科记录, 筛选出胰腺少见病变, 并检索PubMed相应文献并进行总结。结果 共检出胰腺罕见病变6例, 其中胰腺黏液球状体病1例, 浆液性囊腺瘤伴导管腺癌1例, 腺泡细胞囊腺瘤1例, 交界性黏液性囊腺瘤伴黏液样平滑肌肉瘤1例, 破骨细胞样巨细胞瘤1例, 节细胞神经瘤1例。以上病变很少能在PubMed中检索到相关文献, 有些病变甚至找不到与胰腺相关的报道。结论 总结胰腺罕见病例, 有助于更全面地了解胰腺病变, 进一步提高临床诊断水平, 更好地实行个体化诊疗。Abstract:Objective To summarize our experiences in the pathologic diagnosis of rare pancreatic lesions.Methods The clinicopathological data of patients with rare pancreatic lesions which were confirmed in our department from 2000 to 2011 were retrospectively analyzed. Relevant literature retrieved from PubMed was reviewed.Results A total of 6 cases of rare pancreatic lesions were identified, which included myxoglobulosis (n=1), serous cystadenoma associated with ductal adenocarcinoma (n=1), acinar cell cystadenoma (n=1), intermediate mucous cystadenoma associated with mucoid leiomyosarcoma (n=1), osteoclast-like giant cell tumor (n=1) and ganglioneuroma (n=1). Few or no relevant literature was reported in PubMed database.Conclusion Special attention should be paid to these rare pancreatic lesions in clinical practice.