原发性肝血管肉瘤3例病理及文献复习

李霁; 常晓燕; 陈杰; 刘彤华; 杨堤

doi:10.3969/j.issn.1674-9081.2012.01.018

原发性肝血管肉瘤3例病理及文献复习

Primary Hepatic Angiosarcoma: Report of 3 Cases and Literature Review

摘要

摘要:
目的探讨原发性肝血管肉瘤的病理诊断特点, 并复习相关文献。
方法回顾性分析北京协和医院病理科2001年至2010年诊断的3例原发性肝血管肉瘤患者的病理及临床资料。
结果 3例患者的临床表现及影像所见无特异性, 镜下形态多样, 有血管瘤样、上皮样血管内皮细胞瘤样改变, 但均能找到较特异的血管肉瘤诊断特征。
结论原发性肝血管肉瘤是一种罕见的恶性肿瘤, 形态复杂多变。病史、临床症状、影像检查、病理活检的综合运用, 对这一少见恶性肿瘤的诊断十分重要。

Abstract:
Objective To explore the pathological manifestations of primary hepatic angiosarcoma and review the literature.
Methods We retrospectively analyzed the pathological and clinical data of three cases of primary hepatic angiosarcoma, which were confirmed and treated in the Department of Pathology of Peking Union Medical College Hospital from 2001 to 2010.
Results All these three cases showed no specific clinical manifestations and imaging results. Pathologically, there were varies of microscopic patterns such as hemangioma-like and epithelioid hemangioendothelioma-like apperieaces; however, specific pathological diagnostic features of angiosarcoma still existed in all three cases.
Conclusions Primary hepatic angiosarcoma is a rare malignant tumor. The combined application of history-taking, symptom observation, imaging, and liver biopsy is important for the diagnosis of primary hepatic angiosarcoma.

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