光学相干断层扫描技术在皮肤肿瘤中的应用进展

Advances in the Application of Optical Coherence Tomography in Skin Tumors

  • 摘要: 光学相干断层扫描(optical coherence tomography, OCT) 技术是一种兼具无创性、 快速性和实时性的新型成像技术, 其分辨率和穿透深度介于高频超声与反射式共聚焦显微镜之间, 这一独特优势使其在皮肤科领域日益受到重视。 随着技术进步, 新一代 OCT系统通过提升分辨率至亚细胞层级, 并实现微血管网络等精细结构的特征性成像, 显著拓展了其在皮肤病学中的应用范围。 本文系统综述了 OCT 技术在多种皮肤良恶性肿瘤诊断与评估中的应用进展, 重点探讨其在色素痣与黑色素瘤、 基底细胞癌、 鳞状细胞癌、 皮肤附属器肿瘤、 血管瘤及淋巴瘤等疾病中的临床应用价值, 旨在为未来相关研究及临床实践提供理论依据和技术参考。

     

    Abstract: Optical coherence tomography (OCT) is an emerging imaging technology characterized by its non-invasiveness, rapid acquisition, and real-time capabilities. With a resolution and penetration depth intermediate between high-frequency ultrasound and reflectance confocal microscopy, OCT has garnered increasing attention in dermatology. Recent technological advancements have further enhanced OCT systems, achieving subcellular-level resolution and enabling characteristic visualization of microvascular networks and other fine structures, thereby significantly expanding its applications in dermatological practice. This article provides a systematic review of the application progress of OCT technology in the diagnosis and evaluation of various benign and malignant skin tumors. Special emphasis is placed on its clinical utility in melanocytic nevi and melanoma, basal cell carcinoma, squamous cell carcinoma, adnexal tumors, hemangiomas, and lymphomas. The review aims to offer theoretical foundations and technical references for future research and clinical applications in this field.

     

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