Abstract: Primary cutaneous lymphomas are a group of non-Hodgkin's lymphomas originating from the skin, with unique clinical and histological features. In December 2023, the National Comprehensive Cancer Network (NCCN) updated and released the Clinical Practice Guidelines for Primary Cutaneous Lymphomas (Version 1. 2024). Compared to the 2023 edition of the Guidelines, this update mainly focuses on the principles of diagnostic assessment, staging criteria, treatment principles for mycosis fungoides(MF) at different stages, and recommendations for radiotherapy. In conjunction with the current situation and characteristics of the diagnosis and treatment of primary cutaneous lymphoma in our country, this article interprets the main recommendations of the Guidelines to promote the application of clinical practices in our country.