Abstract: As a natural language processing model based on artificial intelligence technology, ChatGPT provides a new path in assisting clinical care implementation, enhancing patient health management and realizing patient intelligent companionship. Given that any technology has two sides, ChatGPT also has potential risks in nursing practice, such as inadequate construction inducing nursing errors, alienated nurse-patient relationship of "digital dependence", and ethical considerations caused by information worries. Therefore, it is suggested to improve the regulatory system, clarify the main body of responsibility, break the "information cocoon", improve digital literacy, control information "streaked", avoid algorithm discrimination and other strategies to improve the application value of ChatGPT in nursing practice and promote the rational development of ChatGPT artificial intelligence in the field of nursing.