Abstract: The Department of Obstetrics and Gynecology of Peking Union Medical College (PUMC) has followed the Johns Hopkins model of combining education, clinical practice and scientific research. The talents cultivated by this model have deeply internalized the concepts of medical science and actively spread modern obstetrics and gynecology, which helps modern obstetrics and gynecology to take roots in China and facilitates their professionalization and institutionalization. This study collected archives, letters, memoirs, newspapers and other materials to investigate the educational, clinical and scientific research work of Obstetrics and Gynecology of PUMC, and on this basis, to explore the characteristics and influence of Obstetrics and Gynecology of PUMC, with the hope of enriching the research of the history of obstetrics and gynecology in China.