From Knowledge to Action: Bridging the Gap Between Theory and Practice in Clinical Practice Guidelines

With the rapid development of evidence-based medicine and clinical practice guidelines, as well as the rise of translational medicine and implementation science, strengthening the translation and utilization of evidence, and promoting the dissemination and implementation of high-quality guidelines has received more and more attention worldwide. In this article, we analyzed and summarized the current status, basic procedures, barriers, and facilitators of guideline dissemination and implementation. Then, we discussed its relationship with the implementation science and how the existing theories, frameworks, models and study designs in the field of implementation science can be used to promote the dissemination and implementation of high-quality guidelines. In the end, we put forward some thoughts and suggestions on how to improve the dissemination and implementation of guidelines in China.