Zhe QU, Zhi-hong WU, Kai-jin GUO. Anticoagulant Therapy for Perioperative Management of Major Lower Limb Joint Surgery[J]. Medical Journal of Peking Union Medical College Hospital, 2019, 10(6): 633-638. DOI: 10.3969/j.issn.1674-9081.2019.06.015
Citation: Zhe QU, Zhi-hong WU, Kai-jin GUO. Anticoagulant Therapy for Perioperative Management of Major Lower Limb Joint Surgery[J]. Medical Journal of Peking Union Medical College Hospital, 2019, 10(6): 633-638. DOI: 10.3969/j.issn.1674-9081.2019.06.015

Anticoagulant Therapy for Perioperative Management of Major Lower Limb Joint Surgery

  • Venous thromboembolism (VTE), comprised of deep vein thrombosis and pulmonary thromboembolism, is a severe complication with a high incidence after major lower limb joint surgery, which has been drawing more of orthopedic surgeons' attention to the preventive treatment. With the development and application of the guidelines of anticoagulant treatment, the risk and the mortality of VTE have been decreased dramatically, and the consensus that anticoagulation is routinely applied to these patients has been reached among orthopedic surgeons. However, controversies remain in the aspects encompassing the choice of specific regimen, short or long course of anticoagulant treatment, the necessity of drug combination, and the anticoagulant plans for those with complex comorbidities. Therefore, the anticoagulant medications, the selection of prophylactic regimen, the risks and complications of anticoagulation, and the optimal anticoagulant plans for complex cases are discussed in the current review.
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