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甲状腺及乳腺多原发癌临床及超声特征

赖兴建 张波 姜玉新 戴晴 朱庆莉

赖兴建, 张波, 姜玉新, 戴晴, 朱庆莉. 甲状腺及乳腺多原发癌临床及超声特征[J]. 协和医学杂志, 2014, 5(1): 22-25. doi: 10.3969/j.issn.1674-9081.2014.01.006
引用本文: 赖兴建, 张波, 姜玉新, 戴晴, 朱庆莉. 甲状腺及乳腺多原发癌临床及超声特征[J]. 协和医学杂志, 2014, 5(1): 22-25. doi: 10.3969/j.issn.1674-9081.2014.01.006
Xing-jian LAI, Bo ZHANG, Yu-xin JIANG, Qing DAI, Qing-li ZHU. Clinical and Ultrasonic Characteristics of Multiple Primary Tumors of Thyroid and Breast[J]. Medical Journal of Peking Union Medical College Hospital, 2014, 5(1): 22-25. doi: 10.3969/j.issn.1674-9081.2014.01.006
Citation: Xing-jian LAI, Bo ZHANG, Yu-xin JIANG, Qing DAI, Qing-li ZHU. Clinical and Ultrasonic Characteristics of Multiple Primary Tumors of Thyroid and Breast[J]. Medical Journal of Peking Union Medical College Hospital, 2014, 5(1): 22-25. doi: 10.3969/j.issn.1674-9081.2014.01.006

甲状腺及乳腺多原发癌临床及超声特征

doi: 10.3969/j.issn.1674-9081.2014.01.006
基金项目: 

国家自然科学基金 81171354

详细信息
    通讯作者:

    姜玉新 电话:010-69155491, E-mail:jiangyuxinxh@163.com

  • 中图分类号: R445.1;R736.1;R737.9

Clinical and Ultrasonic Characteristics of Multiple Primary Tumors of Thyroid and Breast

More Information
  • 摘要:   目的  分析甲状腺及乳腺多原发癌的临床和超声特征。  方法  回顾性分析1990年1月至2013年3月在北京协和医院接受诊治且手术病理证实的甲状腺及乳腺多原发癌24例, 比较这些患者的甲状腺癌及乳腺癌临床和超声特征。  结果  24例患者中9例(37.5%)以甲状腺癌首发, 其中2例(22.2%)在1年内出现乳腺癌; 15例(62.5%)以乳腺癌首发, 其中6例(40.0%)在1年内出现甲状腺癌。甲状腺癌和乳腺癌超声表现均多为实性(86.4%和84.2%)、形态不规则(63.6%和94.7%)、纵横比大于1(50.0%和57.9%)、边界不清(63.6%和78.9%)、低回声或极低回声(90.9%和100%)、点状钙化(50.0%和47.4%)、局部丰富血流(50.0%和68.4%)。  结论  甲状腺及乳腺多原发癌的临床和超声特征与单发甲状腺癌及乳腺癌人群相近, 超声可有效地筛查甲状腺及乳腺多原发癌, 尤其在首发乳腺癌后1年内。
  • 表  1  甲状腺及乳腺多原发癌患者诊断时年龄

    特征 n 诊断时年龄(岁)   间隔(月)
    甲状腺癌   乳腺癌  
    x±s 范围   x±s 范围   x±s 范围
    甲状腺癌首发 9 45.0±14.1 26~72   50.2±13.1 30~72   65.4±53.3 0~168
    乳腺癌首发 15 53.9±7.1 41~68   49.3±8.5 36~67   54.4±62.3 2~171
    下载: 导出CSV

    表  2  甲状腺及乳腺多原发癌病理特征

    甲状腺癌   合并乳腺癌
    病理特征 例(%)   病理特征 例(%)
    乳头状癌 22(91.7)   导管内癌 1(4.2)
          早期浸润性导管癌 3(12.5)
          浸润性导管癌 16(66.7)
          粘液癌 1(4.2)
          髓样癌 1(4.2)
    滤泡癌 1(4.2)   浸润性导管癌 1(4.2)
    髓样癌 1(4.2)   浸润性导管癌 1(4.2)
    下载: 导出CSV

    表  3  甲状腺及乳腺多原发癌临床特征

    肿瘤类型 n 多灶癌
    [例(%)]
    合并症
    [例(%)]
    肿瘤大小
    (cm)
    位置[例(%)]
    左侧 右侧 两侧
    甲状腺癌 22 4(18.2) 15(68.2) 1.1±0.8 8(36.4) 13(59.1) 1(4.5)
    乳腺癌 24 2(8.3) 9(37.5) 2.1±0.9 13(54.2) 11(45.8) 0
    下载: 导出CSV

    表  4  甲状腺及乳腺多原发癌的超声特征[例(%)]

    肿瘤类型 n 实性 形态不规则 纵横比大于1 边界不清 低回声或极低回声 点状钙化 局部丰富血流 转移
    甲状腺癌 22 19(86.4) 14(63.6) 11(50.0) 14(63.6) 20(90.9) 11(50.0) 11(50.0) 3(13.6)
    乳腺癌 19 16(84.2) 18(94.7) 11(57.9) 15(78.9) 19(100) 9(47.4) 13(68.4) 6(31.6)
    下载: 导出CSV
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出版历程
  • 收稿日期:  2013-10-21
  • 刊出日期:  2014-01-30

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