邮件订阅 RSS

留言板

尊敬的读者、作者、审稿人, 关于本刊的投稿、审稿、编辑和出版的任何问题, 您可以本页添加留言。我们将尽快给您答复。谢谢您的支持!

姓名
邮箱
手机号码
标题
留言内容
验证码

Potts分流术治疗顽固性肺动脉高压: 历史与展望

刘鑫裴,  苗齐,  刘剑州

downloadPDF
文章导航 > 协和医学杂志  > 2021 >  12(3): 313-317
刘鑫裴, 苗齐, 刘剑州. Potts分流术治疗顽固性肺动脉高压: 历史与展望[J]. 协和医学杂志, 2021, 12(3): 313-317. doi: 10.12290/xhyxzz.2021-0047
引用本文: 刘鑫裴, 苗齐, 刘剑州. Potts分流术治疗顽固性肺动脉高压: 历史与展望[J]. 协和医学杂志, 2021, 12(3): 313-317. doi: 10.12290/xhyxzz.2021-0047
shu
LIU Xinpei, MIAO Qi, LIU Jianzhou. Potts Shunt for Refractory Pulmonary Hypertension: Historical and Future Perspectives[J]. Medical Journal of Peking Union Medical College Hospital, 2021, 12(3): 313-317. doi: 10.12290/xhyxzz.2021-0047
Citation: LIU Xinpei, MIAO Qi, LIU Jianzhou. Potts Shunt for Refractory Pulmonary Hypertension: Historical and Future Perspectives[J]. Medical Journal of Peking Union Medical College Hospital, 2021, 12(3): 313-317. doi: 10.12290/xhyxzz.2021-0047
shu

Potts分流术治疗顽固性肺动脉高压: 历史与展望

doi: 10.12290/xhyxzz.2021-0047

  • 中国医学科学院 北京协和医学院 北京协和医院心外科，北京 100730

详细信息
    通讯作者:

    苗齐  电话：010-69152829，E-mail: miaoqipumc@hotmail.com

  • 中图分类号: R541;R654.2

Potts Shunt for Refractory Pulmonary Hypertension: Historical and Future Perspectives

  • Department of Cardiac Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

More Information

    摘要
  • 摘要: 肺动脉高压是继发于先天性心脏病、肺血管病变、肺栓塞或因特发性疾病导致的以肺动脉压力升高为特点的疾病。充分靶向药物降压治疗下仍进展的顽固性肺动脉高压需手术干预，传统的肺移植或心肺联合移植手术面临供体有限、配型困难、免疫排斥等诸多问题。在此背景下，以建立心外体肺分流、缓解致命性右心衰竭为目的的Potts分流术逐渐复兴，但其用于治疗顽固性肺动脉高压的历史尚短，开展范围尚小，具体的适应证、禁忌证、手术策略及远期预后仍需更多循证医学证据支持。本文以Potts分流术的历史为线索，对该术式的优势、未来应用前景及尚未解决的关键问题进行论述。
    Abstract: Pulmonary artery hypertension (PAH) is a disease secondary to congenital heart diseases, pulmonary vascular disorders, embolism, or idiopathic reasons. Surgery is necessary for PAH refractory to modern combined medical therapy. Results of lung transplantation are limited by factors like donor shortage, matching difficulty, immune rejection, etc. In order to make an extracardiac shunt to release the deadly right ventricular failure, the old Potts shunt surgery has enjoyed a recent revival. Although some early and mid-term results are satisfactory, the history of Potts shunt surgery in the treatment of refractory PAH is short and the sample size is limited. More proofs of medical research are needed for its specific indications, details of surgical strategies, and long-term prognosis. Based on its origin and development in the treatment of PAH, this paper reviews the advantages, future directions and unsolved key problems of Potts shunt surgery.
    作者贡献:  作者贡献：刘鑫裴负责查阅文献、撰写论文; 苗齐负责选题设计、修订、审核论文; 刘剑州负责修订论文。
    利益冲突:   无
    • HTML全文
    • 参考文献(19)
  • [1] Baruteau AE, Serraf A, Levy M, et al. Potts shunt in children with idiopathic pulmonary arterial hypertension: long-term results[J]. Ann Thorac Surg, 2012, 94: 817-824. doi:  10.1016/j.athoracsur.2012.03.099
    [2] D'Alonzo GE, Barst RJ, Ayres SM, et al. Survival in patients with primary pulmonary hypertension. Results from a national prospective registry[J]. Ann Intern Med, 1991, 115: 343-349. doi:  10.7326/0003-4819-115-5-343
    [3] Rossano JW, Singh TP, Cherikh WS, et al. The Interna-tional Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Twenty-second pediatric heart transplantation report-2019; Focus theme: Donor and recipient size match[J]. J Heart Lung Transplant, 2019, 38: 1028-1041. doi:  10.1016/j.healun.2019.08.002
    [4] Rich S, Lam W. Atrial septostomy as palliative therapy for refractory primary pulmonary hypertension. [J] Am J Cardiol, 1983, 51: 1560-1561. doi:  10.1016/0002-9149(83)90678-1
    [5] Cantor WJ, Harrison DA, Moussadji JS, et al. Deter-minants of survival and length of survival in adults with Eisenmenger syndrome[J]. Am J Cardiol, 1999, 84: 677-681. doi:  10.1016/S0002-9149(99)00415-4
    [6] Blanc J, Vouhe P, Bonnet D. Potts shunt in patients with pulmonary hypertension[J]. N Engl J Med, 2004, 350: 623. doi:  10.1056/NEJM200402053500623
    [7] Baruteau AE, Belli E, Boudjemline Y, et al. Palliative Potts shunt for the treatment of children with drug-refractory pulmonary arterial hypertension: updated data from the first 24 patients[J]. Eur J Cardiothorac Surg, 2015, 47: e105-e110. doi:  10.1093/ejcts/ezu445
    [8] Lancaster TS, Shahanavaz S, Balzer DT, et al. Midterm outcomes of the Potts shunt for pediatric pulmonary hyperten-sion, with comparison to lung transplant[J]. J Thorac Cardiovasc Surg, 2021, 161: 1139-1148. doi:  10.1016/j.jtcvs.2020.10.163
    [9] Hansmann G, Koestenberger M, Alastalo TP, et al. 2019 updated consensus statement on the diagnosis and treatment of pediatric pulmonary hypertension: The European Pediatric Pulmonary Vascular Disease Network (EPPVDN), endorsed by AEPC, ESPR and ISHLT[J]. J Heart Lung Transplant, 2019, 38: 879-901. doi:  10.1016/j.healun.2019.06.022
    [10] Thangappan K, Morales DLS. Commentary: To transplant or not to transplant: Potts shunt as an alternative to pediatric lung transplantation[J]. J Thorac Cardiovasc Surg, 2021, 161: 1149-1150. doi:  10.1016/j.jtcvs.2020.11.062
    [11] Grady RM, Eghtesady P. Potts Shunt and Pediatric Pulmonary Hypertension: What We Have Learned[J]. Ann Thorac Surg, 2016, 101: 1539-1543. doi:  10.1016/j.athoracsur.2015.08.068
    [12] Sabi TM, Schmitt B, Sigler M, et al. Transcatheter creation of an aortopulmonary shunt in an animal model[J]. Catheter Cardiovasc Interv, 2010, 75: 563-569. http://new.med.wanfangdata.com.cn/Paper/Detail?id=PeriodicalPaper_JJ0217568038
    [13] Esch JJ, Shah PB, Cockrill BA, et al. Transcatheter Potts shunt creation in patients with severe pulmonary arterial hypertension: initial clinical experience[J]. J Heart Lung Transplant, 2013, 32: 381-387. doi:  10.1016/j.healun.2013.01.1049
    [14] Boudjemline Y, Patel M, Malekzadeh-Milani S, et al. Patent ductus arteriosus stenting (transcatheter Potts shunt) for palliation of suprasystemic pulmonary arterial hyperten-sion: a case series[J]. Circ Cardiovasc Interv, 2013, 6: e18-e20.
    [15] Boudjemline Y, Sizarov A, Malekzadeh-Milani S, et al. Safety and Feasibility of the Transcatheter Approach to Create a Reverse Potts Shunt in Children With Idiopathic Pulmonary Arterial Hypertension[J]. Can J Cardiol, 2017, 33: 1188-1196. doi:  10.1016/j.cjca.2017.06.004
    [16] Ratnayaka K, Rogers T, Schenke WH, et al. Magnetic Resonance Imaging-Guided Transcatheter Cavopulmonary Shunt[J]. JACC Cardiovasc Interv, 2016, 9: 959-970. doi:  10.1016/j.jcin.2016.01.032
    [17] Bui MT, Grollmus O, Ly M, et al. Surgical palliation of primary pulmonary arterial hypertension by a unidirectional valved Potts anastomosis in an animal model[J]. J Thorac Cardiovasc Surg, 2011, 142: 1223-1228. doi:  10.1016/j.jtcvs.2010.10.060
    [18] Rosenzweig EB, Ankola A, Krishnan U, et al. A novel unidirectional-valved shunt approach for end-stage pulmonary arterial hypertension: Early experience in adolescents and adults[J]. J Thorac Cardiovasc Surg, 2021, 161: 1438-1446. e2. doi:  10.1016/j.jtcvs.2019.10.149
    [19] Garekar S, Meeran T, Dhake S, et al. Valved reverse Potts shunt in a case of pulmonary hypertension due to pulmonary veno-occlusive disease[J]. Indian J Thorac Cardiovasc Surg, 2021, 37: 89-92. doi:  10.1007/s12055-020-00993-2
    • 相关文章
    • 施引文献
  • 资源附件(0)
  • 加载中
WeChat 点击查看大图
计量
  • 文章访问数:  1362
  • HTML全文浏览量:  318
  • PDF下载量:  156
  • 被引次数: 0
出版历程
  • 收稿日期:  2021-01-14
  • 录用日期:  2021-03-23
  • 刊出日期:  2021-05-30

目录

    /

    返回文章
    返回
    友情链接: 国家卫生健康委员会 北京协和医院 中国医学科学院 学术不端检测系统 国际知识资源总库 中国知网 术语在线 中国全科医学
    地址：北京市东城区帅府园1号 北京协和医院老楼7号楼
    3层302室 《协和医学杂志》编辑部
    电话：010-69154261/4262
    E - mail：medj@pumch.cn
    mjpumch@126.com
    期刊网站版权所有：《协和医学杂志》编辑部
    京ICP备 11002662

    本系统由 北京仁和汇智信息技术有限公司 开发    百度统计

    x 关闭 永久关闭

    【温馨提醒】近日，《协和医学杂志》编辑部接到作者反映，有多名不法人员冒充期刊编辑发送见刊通知，鼓动作者添加微信，从而骗取版面费的行为。特提醒您，本刊与作者联系的方式均为邮件通知或电话，稿件进度通知邮箱为：mjpumch@126.com，编辑部电话为：010-69154261，请提高警惕，谨防上当受骗！如有任何疑问，请致电编辑部核实。谢谢！