Volume 11 Issue 6
Nov.  2020
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LIU Jie, LUO Yi-xin, LIU Zhao-rui, LIU Yue-hua, ZHANG Wei, LU Zhao-hui. WHO-EORTC Classification of Primary Cutaneous Lymphomas:Updates and Interpretation[J]. Medical Journal of Peking Union Medical College Hospital, 2020, 11(6): 698-702. doi: 10.3969/j.issn.1674-9081.2020.06.011
Citation: LIU Jie, LUO Yi-xin, LIU Zhao-rui, LIU Yue-hua, ZHANG Wei, LU Zhao-hui. WHO-EORTC Classification of Primary Cutaneous Lymphomas:Updates and Interpretation[J]. Medical Journal of Peking Union Medical College Hospital, 2020, 11(6): 698-702. doi: 10.3969/j.issn.1674-9081.2020.06.011

WHO-EORTC Classification of Primary Cutaneous Lymphomas:Updates and Interpretation

doi: 10.3969/j.issn.1674-9081.2020.06.011
Funds:

The National Key Research and Development Program of China 2016YFC0901500

Beijing Natural Science Foundation 7182127

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  • Corresponding author: LIU Jie  Tel: 86-10-69151536, E-mail: Liujie04672@pumch.cn
  • Received Date: 2020-04-23
  • Accepted Date: 2020-06-02
  • Available Online: 2020-06-02
  • Publish Date: 2020-11-30
  • Primary cutaneous lymphomas (PCL) are a group of non-Hodgkin's lymphomas that are presented with specific clinical manifestations and histopathological characteristics. The classification of PCL published by World Health Organization-European Organization for Research and Treatment of Cancer (WHO-EORTC) in 2005 was the important diagnostic criteria and classification basis for cutaneous lymphomas. With research progression, WHO-EORTC updated the classification of PCL in 2018, adding three subtypes of PCL, namely, chronic active Epstein Barr virus (EBV) infection, primary cutaneous acral CD8+ T-cell lymphoma, and EBV-positive mucocutaneous ulcer. Besides, some subtypes of PCL were revised, including lymphomatoid papulosis, primary cutaneous marginal zone lymphoma, and primary cutaneous CD4+ small/medium T cell lymphoproliferative disease. This article interprets the update of WHO-EORTC classification of PCL.
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