Volume 11 Issue 4
Jul.  2020
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Qing-xing LIU, Jie ZANG, Jia-kun REN, Zhao-hui ZHU. Radionuclide Imaging and Therapy of Neuroendocrine Neoplasm by Targeting the Somatostatin Receptor[J]. Medical Journal of Peking Union Medical College Hospital, 2020, 11(4): 370-376. doi: 10.3969/j.issn.1674-9081.2020.04.003
Citation: Qing-xing LIU, Jie ZANG, Jia-kun REN, Zhao-hui ZHU. Radionuclide Imaging and Therapy of Neuroendocrine Neoplasm by Targeting the Somatostatin Receptor[J]. Medical Journal of Peking Union Medical College Hospital, 2020, 11(4): 370-376. doi: 10.3969/j.issn.1674-9081.2020.04.003

Radionuclide Imaging and Therapy of Neuroendocrine Neoplasm by Targeting the Somatostatin Receptor

doi: 10.3969/j.issn.1674-9081.2020.04.003
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  • Corresponding author: ZHU Zhao-hui Tel: 86-10-69154196, E-mail:13611093752@163.com
  • Received Date: 2020-04-10
  • Publish Date: 2020-07-30
  • Neuroendocrine neoplasm (NEN) is a heterogeneous group of tumors characterized by neuroendocrine differentiation. Most of the tumor cells show high-level expression of the somatostatin receptor (SSTR), which provides an important target for molecular imaging and peptide receptor radionuclide therapy (PRRT). This area has become a research hotspot at home and abroad in recent years. In addition, rapid progress and new breakthroughs have been made in clinical translation and application continuously. This article reviewed the new advances in SSTR-targeted nuclear molecular imaging and PRRT, and summarized their main advantages and important values in the diagnosis and treatment of NEN, in hope of giving relevant professional doctors a reference for clinical diagnosis and treatment.
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