Volume 10 Issue 2
Sep.  2020
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Yu-yue ZHAO, Hao WANG, Zhao-hui ZHU, Zuo-jun XU. A Case of Sarcoidosis with Asymptomatic Cardiac Involvement[J]. Medical Journal of Peking Union Medical College Hospital, 2019, 10(2): 185-188. doi: 10.3969/j.issn.1674-9081.2019.02.019
Citation: Yu-yue ZHAO, Hao WANG, Zhao-hui ZHU, Zuo-jun XU. A Case of Sarcoidosis with Asymptomatic Cardiac Involvement[J]. Medical Journal of Peking Union Medical College Hospital, 2019, 10(2): 185-188. doi: 10.3969/j.issn.1674-9081.2019.02.019

A Case of Sarcoidosis with Asymptomatic Cardiac Involvement

doi: 10.3969/j.issn.1674-9081.2019.02.019
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  • Corresponding author: XU Zuo-jun Tel:010-69155039, E-mail: xuzj@hotmail.com
  • Received Date: 2017-12-14
  • Publish Date: 2020-09-18
  • Sarcoidosis is a multi-system inflammatory disorder with the characteristics of non-caseating granulomas, which is most commonly involved in lungs, heart, eyes, skin, and other organs. Symptomatic cardiac involvement is found in about 2%~5% of sarcoidosis patients. However, autopsy studies have detected that approximately 25%~50% of sarcoidosis patients have asymptomatic cardiac involvement with a delayed diagnosis and poor prognosis. We report the clinical manifestations, laboratory examinations, diagnostic methods, and treatment of one sarcoidosis patient with latent cardiac involvement, to remind clinicians to pay attention to the systematic evaluation of sarciodosis.
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  • [1] Valeyre D, Prasse A, Nunes H, et al. Sarcoidosis[J]. Lancet, 2014, 383: 1155-1167. doi:  10.1016/S0140-6736(13)60680-7
    [2] Dubrey SW, Falk RH. Diagnosis and management of cardiac sarcoidosis[J]. Prog Cardiovasc Dis, 2010, 52: 336-346. doi:  10.1016/j.pcad.2009.11.010
    [3] Ardehali H, Howard DL, Hariri A, et al. A positive endomyocardial biopsy result for sarcoid is associated with poor prognosis in patients with initially unexplained cardiomyopathy[J]. Am Heart J, 2005, 150: 459-463. doi:  10.1016/j.ahj.2004.10.006
    [4] Iwai K, Takemura T, Kitaichi M, et al. Pathological studies on sarcoidosis autopsy Ⅱ. Early change, mode of progression and death pattern[J]. Acta Pathol Jpn, 1993, 43: 377-385. doi:  10.1111/j.1440-1827.1993.tb01149.x
    [5] Birnie DH, Kandolin R, Nery PB, et al. Cardiac manifestations of sarcoidosis: diagnosis and management[J]. Eur Heart J, 2017, 38:2663-2670.
    [6] Cooper LT, Baughman KL, Feldman AM, et al. The role of endomyocardial biopsy in the management of cardiovascular disease: a scientific statement from the American Heart Association, the American College of Cardiology, and the European Society of Cardiology. Endorsed by the Heart Failure Society of America and the Heart Failure Association of the European Society of Cardiology[J]. J Am Coll Cardiol, 2007, 50: 1914-1931. doi:  10.1016/j.jacc.2007.09.008
    [7] Simonen P, Lehtonen J, Kandolin R, et al. F-18-fluorodeoxyglucose positron emission tomography-guided sampling of mediastinal lymph nodes in the diagnosis of cardiac sarcoidosis[J]. Am J Cardiol, 2015, 116: 1581-1585. doi:  10.1016/j.amjcard.2015.08.025
    [8] Ishimaru S, Tsujino I, Takei T, et al. Focal uptake on 18F-fluoro-2-deoxyglucose positron emission tomography images indicates cardiac involvement of sarcoidosis[J]. Eur Heart J, 2005, 26: 1538-1543. doi:  10.1093/eurheartj/ehi180
    [9] Blankstein R, Osborne M, Naya M, et al. Cardiac positron emission tomography enhances prognostic assessments of patients with suspected cardiac sarcoidosis[J]. J Am Coll Cardiol, 2014, 63: 329-336. doi:  10.1016/j.jacc.2013.09.022
    [10] Birnie DH, Sauer WH, Bogun F, et al. HRS expert consensus statement on the diagnosis and management of arrhythmias associated with cardiac sarcoidosis[J]. Heart Rhythm, 2014, 11: 1304-1323. doi:  10.1016/j.hrthm.2014.03.043
    [11] Nery PB, Beanlands RS, Nair GM, et al. Atrioventricular block as the initial manifestation of cardiac sarcoidosis in middle-aged adults[J]. J Cardiovasc Electrophysiol, 2014, 25: 875-881. doi:  10.1111/jce.12401
    [12] Kumar S, Barbhaiya C, Nagashima K, et al. Ventricular tachycardia in cardiac sarcoidosis: characterization of ventricular substrate and outcomes of catheter ablation[J]. Circ Arrhythm Electrophysiol, 2015, 8: 87-93. doi:  10.1161/CIRCEP.114.002145
    [13] Jeudy J, Burke AP, White CS, et al. Cardiac sarcoidosis: the challenge of radiologic-pathologic correlation: from the radiologic pathology archives[J]. Radiographics, 2015, 35: 657-679. doi:  10.1148/rg.2015140247
    [14] Baughman RP, Engel PJ, Nathan S. Pulmonary Hypertension in Sarcoidosis[J]. Clin Chest Med, 2015, 36: 703-714. doi:  10.1016/j.ccm.2015.08.011
    [15] Kinney E, Murthy R, Ascunce G, et al. Pericardial effusions in sarcoidosis[J]. Chest, 1979, 76: 476-478. doi:  10.1378/chest.76.4.476
    [16] Barton JH, Tavora F, Farb A, et al. Unusual cardiovascular manifestations of sarcoidosis, a report of three cases: coronary artery aneurysm with myocardial infarction, symptomatic mitral valvular disease, and sudden death from ruptured splenic artery[J]. Cardiovasc Pathol, 2010, 19: e119-e123. doi:  10.1016/j.carpath.2009.04.006
    [17] Weiler V, Redtenbacher S, Bancher C, et al. Concurrence of sarcoidosis and aortitis: case report and review of the literature[J]. Ann Rheum Dis, 2000, 59: 850-853. doi:  10.1136/ard.59.11.850
    [18] Hulten E, Aslam S, Osborne M, et al. Cardiac sarcoidosis-state of the art review[J]. Cardiovasc Diagn Ther, 2016, 6: 50-63.
    [19] Hunninghake GW, Costabel U, Ando M, et al. ATS/ERS/WASOG statement on sarcoidosis. American Thoracic Society/European Respiratory Society/World Association of Sarcoido-sis and other Granulomatous Disorders[J]. Sarcoidosis Vasc Diffuse Lung Dis, 1999, 16: 149-173.
    [20] Young L, Sperry BW, Hachamovitch R. Update on Treatment in Cardiac Sarcoidosis[J]. Curr Treat Options Cardiovasc Med, 2017, 19: 47. doi:  10.1007/s11936-017-0539-1
    [21] Fahim A, Mann JS. Pulmonary sarcoidosis: diagnostic and treatment update[J]. Expert Rev Respir Med, 2014, 8: 493-501. doi:  10.1586/17476348.2014.919225
    [22] Baughman RP, Iannuzzi MC, Lower EE, et al. Use of fluticasone in acute symptomatic pulmonary sarcoidosis[J]. Sarcoidosis Vasc Diffuse Lung Dis, 2002, 19: 198-204. http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=3beb634e52caab39af58b7cc71826b52
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