Jing YANG, Yao CHEN, Yan KANG. One Postoperative Patient with Severe Acute Pancreatitis Complicated with Persistent Hypotension[J]. Medical Journal of Peking Union Medical College Hospital, 2018, 9(5): 463-366. doi: 10.3969/j.issn.1674-9081.2018.05.017
Citation: Jing YANG, Yao CHEN, Yan KANG. One Postoperative Patient with Severe Acute Pancreatitis Complicated with Persistent Hypotension[J]. Medical Journal of Peking Union Medical College Hospital, 2018, 9(5): 463-366. doi: 10.3969/j.issn.1674-9081.2018.05.017

One Postoperative Patient with Severe Acute Pancreatitis Complicated with Persistent Hypotension

doi: 10.3969/j.issn.1674-9081.2018.05.017
More Information
  • Corresponding author: KANG Yan   Tel:028-85422739, E-mail:kangyan@scu.edu.cn
  • Received Date: 2018-07-04
  • Publish Date: 2018-09-30
  • The aim of this article was to explore the diagnostic approach and treatment of persistent hypotension in postoperative patients with severe acute pancreatitis(SAP). The diagnostic approach and treatment were summarized through retrospectively analyzing the clinical data of one SAP patient with persistent postoperative hypotension. This was a 61 years old male SAP patient and was transferred to the department of critical care medicine after surgery. Hypovolemic shock and infection, the initial features of this patient, were controlled after resuscitation and anti-infective therapy. But the patient still had persistent hypotension. All types of shock were distinguished and hormone examination was performed. The patient was finally diagnosed as critical illness-related corticosteroid insufficiency(CIRCI). The symptom of persistent hypotension was significantly improved after hormone replacement. At the one-month follow-up, the patient's blood pressure returned to normal and then hormone therapy was stopped. The possibility of CIRCI should be taken into account when a SAP patient with unexplained persistent postoperative hypotension after the successful control for infection. Early diagnosis and glucocorticoid replacement therapy is helpful for the recovery of the patients.
  • loading
  • [1] Buter A, Imrie CW, Carter CR, et al. Dynamic nature of early organ dysfunction determines outcome in acute pancreatitis[J]. Br J Surg, 2002, 89: 298-302. doi:  10.1046/j.0007-1323.2001.02025.x
    [2] Halonen KI, Pettilä V, Leppäniemi AK, et al. Multiple organ dysfunction associated with severe acute pancreatitis[J]. Crit Care Med, 2002, 30: 1274-1279. doi:  10.1097/00003246-200206000-00019
    [3] Majidi S, Golembioski A, Wilson SL, et al. Acute Pancreatitis: Etiology, Pathology, Diagnosis, and Treatment[J]. South Med J, 2017, 110: 727-732. doi:  10.14423/SMJ.0000000000000727
    [4] Uhl W, Warshaw A, Imrie C, et al. LAP Guidelines for the Surgical Management of Acute Pancreatitis[J]. Pancreatology, 2002, 2: 565-573. doi:  10.1159/000067684
    [5] Singer M, Deutschman CS, Seymour CW, et al. The third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)[J]. JAMA, 2016, 315:801-810. doi:  10.1001/jama.2016.0287
    [6] Annane D, Pastores SM, Rochwerg B, et al.Guidelines for the diagnosis and management of critical illness-related corticosteroid insufficiency (CIRCI) in critically ill patients (Part Ⅰ): Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM) 2017[J]. Intensive Care Med, 2018, 44:401-402. doi:  10.1007/s00134-018-5071-6
    [7] Pastores SM, Annane D, Rochwerg B, et al. Guidelines for the Diagnosis and Management of Critical Illness-Related Corticosteroid Insufficiency (CIRCI) in Critically Ⅲ Patients (Part Ⅱ): Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM) 2017[J]. Crit Care Med, 2018, 46:146-148.
    [8] Fleseriu M, Hashim IA, Karavitaki N, et al. Hormonal Replacement in Hypopituitarism in Adults: An Endocrine Society Clinical Practice Guideline[J]. J Clin Endocrinol Metab, 2016, 101:3888-3921. doi:  10.1210/jc.2016-2118
    [9] Yanase T, Tajima T, Katabami T, et al. Diagnosis and treatment of adrenal insufficiency including adrenal crisis: a Japan Endocrine Society clinical practice guideline[J]. Endocr J, 2016, 63:765-784. doi:  10.1507/endocrj.EJ16-0242
    [10] Gibbison B, López-López JA, Higgins JP, et al. Corticos-teroids in septic shock: a systematic review and network meta-analysis[J]. Crit Care, 2017, 21:78. doi:  10.1186/s13054-017-1659-4
    [11] Annane D, Bellissant E, Bollaert PE, et al. Corticos-teroids in the treatment of severe sepsis and septic shock in adults: a systematic review[J]. JAMA, 2009, 301:2362-2375. doi:  10.1001/jama.2009.815
    [12] Annane D, Renault A, Brun-Buisson C, et al. Hydro-cortisone plus Fludrocortisone for Adults with Septic Shock[J]. N Engl J Med, 2018, 378:809-818. doi:  10.1056/NEJMoa1705716
    [13] Bhatia M, Wong FL, Cao Y, et al. Pathophysiology of acute pancreatitis[J]. Pancreatology, 2005, 5:132-144. doi:  10.1159/000085265
    [14] Arlt W, Hammer F, Sanning P, et al. Dissociation of serum dehydroepiandrosterone and dehydroepiandrosterone sulfate in septic shock[J]. J Clin Endocrinol Metab, 2006, 91:2548-2554. doi:  10.1210/jc.2005-2258
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Tables(1)

    Article Metrics

    Article views (241) PDF downloads(107) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return