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Article Navigation >  Medical Journal of Peking Union Medical College Hospital  > 2018  >  9(4): 289-294
Han-zhong LI, Yu-shi ZHANG, Guo-yang ZHENG. Commentary on and Expectation of Tumor Immunotherapy[J]. Medical Journal of Peking Union Medical College Hospital, 2018, 9(4): 289-294. doi: 10.3969/j.issn.1674-9081.2018.04.001
Citation: Han-zhong LI, Yu-shi ZHANG, Guo-yang ZHENG. Commentary on and Expectation of Tumor Immunotherapy[J]. Medical Journal of Peking Union Medical College Hospital, 2018, 9(4): 289-294. doi: 10.3969/j.issn.1674-9081.2018.04.001
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Commentary on and Expectation of Tumor Immunotherapy

doi: 10.3969/j.issn.1674-9081.2018.04.001

  • Department of Urology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

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  • Corresponding author: 李汉忠 电话:010-69152510, E-mail:hzlipumch@163.com LI Han-zhong Tel:010-69152510, E-mail:hzlipumch@163.com
  • Received Date: 2018-04-11
  • Publish Date: 2018-07-30
    Abstract
  • With the rapid development of tumor immunology, immunotherapy for malignant tumors is becoming a research focus, offering an effective opportunity for the treatment of patients with advanced tumors. Immune checkpoint inhibitors, such as programmed cell death 1 receptor/programmed cell death 1 ligand 1 antibody and CTLA-4 antibody, are an important research hotspot of immunotherapy for advanced cancers. FDA has approved some immune checkpoint antibodies for the treatment of advanced metastatic melanoma, non-small cell lung cancer, renal cell carcinoma, uroepithelium carcinoma, and non-Hodgkin's lymphoma, and the efficacy and safety for above tumors has been confirmed. In addition, chemiric antigen receptor T-cell therapy treatment showed a strong and persistent therapeutic effect for hematologic malignancy, as another successful case of immunotherapy. Cancer vaccine such as Simpuleucel-T was also another milestone in the development of tumor immunotherapy. Currently, immunotherapy for malignant tumors is presenting a promising future.
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