Clinical Outcome of Mitral Valve Repair for Non-ischemic Mitral Regurgitation

  Objective  To evaluate the clinical outcome of mitral valve repair for non-ischemic mitral regurgitation.

  Methods  We reviewed the clinical data of 104 consecutive patients with non-ischemic mitral regurgitation who underwent elective mitral valvuloplasty from January 2001 to December 2012 in Peking Union Medical College Hospital. The enrolled patients included 58 men and 46 women, aged (45.3±16.8)years (range, 9-77 years). The surgical procedures were elective mitral valvuloplasty with cardiopulmonary bypass, during which the mitral leaflets were repaired and annuloplastic rings of appropriate sizes were implanted.

  Results  The success rate of surgery was 96.2% (100/104). One patient died postoperatively due to multiple organ failure (mortality 0.96%). One patient developed renal failure which mandated transient renal replacement therapy. The median follow-up time was 46 months(range, 8-141 months) and 8 patients were lost. One late death occurred due to neoplasia. Three patients suffered relapse of mitral regurgitation, of whom two underwent mitral replacement. The rate of freedom from mitral regurgitation was 96.7% (88/91), and the rate of freedom from re-operation was 97.8% (89/91).

  Conclusions  With satisfactory short- and long-term outcomes, mitral valvuloplasty could be the primary treatment for non-ischemic mitral regurgitation.