Spectral-domain Optical Coherence Tomography Findings of Choroidal Thickness in Eyes of Patients with Idiopathic Macular Holes

  Objective  To determine the choroidal thickness in the eyes with idiopathic macular hole (IMH) and the unaffected fellow eyes.

  Methods  Twenty IMH patients and 20 ageand sex-matched healthy controls were recruited. Enhanced depth images were obtained using spectal-domain optical coherence tomography. The choroidal thickness was measured in the subfoveal area and 1 mm and 2 mm away from the fovea in the nasal, temporal, superior and inferior regions.

  Results  The mean subfoveal area choroidal thickness was (161.53±50.50) μm in the eyes with IMH, (204.95±59.58) μm in the fellow eyes, and (248.00±63.40) μm in the control group (P=0.000). The choroidal thickness at all measured regions showed significant differences among three groups (P < 0.05). Compared with the control group, the choroidal thickness was significantly thinner in eyes with IMH (P < 0.01) and unaffected fellow eyes except for the superior choroidal thickness at 2 mm and inferior choroidal thickness at 2 mm (P < 0.05).

  Conclusion  Choroidal thickness decreases in eyes with IMH and may also reduce in the unaffected fellow eyes, suggesting that the development of IMH may be associated with the choroid perfusion.