Use of Moxifloxacin Injection for Inpatients in Peking Union Medical College Hospital

  Objective  To analyze the recent use of moxifloxacin injection in a tertiary hospital in Beijing.

  Methods  The use of moxifloxacin injection among inpatients in Peking Union Medical College Hospital in 2010 and the first quarter of 2011 was analyzed based on the hospital information system database. Meanwhile, the clinical records of 53 patients were reviewed for relevant data including medication purpose, dosage, and surgical procedures.

  Results  Compared to the first quarter of 2010, the total usage of moxifloxacin injection increased by 5.15% and the preoperative prophylaxis usage by 20.51% in the first quarter of 2011. The individual consumption also showed a growing tendency(P=0.003). With the number of patients younger than 18 years increased from 2 in the first quarter of 2010 to 6 in the first quarter of 2011. Of 45 patients who had preoperatively received moxifloxacin, 39 (86.7%) were for prophylaxis purpose. Of 21 patients with infectious diseases, etiological inspection was performed in 11 patients (52.38%).

  Conclusion  Moxifloxacin injection has been widely used in our hospital. However, its administration is not always rational, especially when applied for preoperative prophylaxis.