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Chun-xia HE, Ya-gang ZUO, Ming YANG, Li LI, Kai FANG. Role of Direct Immunofluorescence in Diagnosis of Autoimmune Bullous Dermatoses: a Retrospective Analysis of 155 Cases[J]. Medical Journal of Peking Union Medical College Hospital, 2012, 3(4): 402-405. DOI: 10.3969/j.issn.1674-9081.2012.04.009
Citation: Chun-xia HE, Ya-gang ZUO, Ming YANG, Li LI, Kai FANG. Role of Direct Immunofluorescence in Diagnosis of Autoimmune Bullous Dermatoses: a Retrospective Analysis of 155 Cases[J]. Medical Journal of Peking Union Medical College Hospital, 2012, 3(4): 402-405. DOI: 10.3969/j.issn.1674-9081.2012.04.009
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Role of Direct Immunofluorescence in Diagnosis of Autoimmune Bullous Dermatoses: a Retrospective Analysis of 155 Cases

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    • Abstract
  •   Objective  To explore the diagnostic value of direct immunofluorescence (DIF) for autoimmune bullous dermatoses (AIBD).
      Methods  The DIF features were reviewed in 155 AIBD patients who were admitted to Peking Union Medical College Hospital from January 2009 to December 2011. The diagnostic sensitivity of DIF was compared with that of histopathologic examination.
      Results  Various types of AIBD showed different DIF features. The diagnostic sensitivity of DIF was 92.9%, which showed no significant difference with that of histopathologic findings (85.2%) (χ2=2.063, P=0.058).
      Conclusion  DIF plays a significant role in the diagnosis and differential diagnosis of AIBD.
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