Primary Hepatic Angiosarcoma: Report of 3 Cases and Literature Review

  Objective  To explore the pathological manifestations of primary hepatic angiosarcoma and review the literature.

  Methods  We retrospectively analyzed the pathological and clinical data of three cases of primary hepatic angiosarcoma, which were confirmed and treated in the Department of Pathology of Peking Union Medical College Hospital from 2001 to 2010.

  Results  All these three cases showed no specific clinical manifestations and imaging results. Pathologically, there were varies of microscopic patterns such as hemangioma-like and epithelioid hemangioendothelioma-like apperieaces; however, specific pathological diagnostic features of angiosarcoma still existed in all three cases.

  Conclusions  Primary hepatic angiosarcoma is a rare malignant tumor. The combined application of history-taking, symptom observation, imaging, and liver biopsy is important for the diagnosis of primary hepatic angiosarcoma.