Objective To investigate the clinicopathological features of solitary desmoplastic fibroma of the bone (DF).
Methods Totally 4 cases of DF were confirmed in our hospital from October 2004 to July 2008. Their clinical manifestations as well as the pathologic, morphologic, and immunohistochemical findings were summarized, and relevelant literature was reviewed.
Results DF was composed of spindle cells (fibroblasts/myofibroblasts) in a background of numerous thick and wavy collagen fibers of ovoid nuclei dispersed within a collagenous fibers. No mitotic figures, hypercellularity, or pleomorphism was observed.
Conclusion DF is a rare benign lesion and can be progressive, invasive, and sometimes recurrent.