Ying JIANG, Xiao-yan CHANG, Jie SHI, Quan-cai CUI. Clinicopathological Features of Desmoplastic Fibroma of the Bone[J]. Medical Journal of Peking Union Medical College Hospital, 2012, 3(1): 47-50. DOI: 10.3969/j.issn.1674-9081.2012.01.011
Citation: Ying JIANG, Xiao-yan CHANG, Jie SHI, Quan-cai CUI. Clinicopathological Features of Desmoplastic Fibroma of the Bone[J]. Medical Journal of Peking Union Medical College Hospital, 2012, 3(1): 47-50. DOI: 10.3969/j.issn.1674-9081.2012.01.011

Clinicopathological Features of Desmoplastic Fibroma of the Bone

  •   Objective  To investigate the clinicopathological features of solitary desmoplastic fibroma of the bone (DF).
      Methods  Totally 4 cases of DF were confirmed in our hospital from October 2004 to July 2008. Their clinical manifestations as well as the pathologic, morphologic, and immunohistochemical findings were summarized, and relevelant literature was reviewed.
      Results  DF was composed of spindle cells (fibroblasts/myofibroblasts) in a background of numerous thick and wavy collagen fibers of ovoid nuclei dispersed within a collagenous fibers. No mitotic figures, hypercellularity, or pleomorphism was observed.
      Conclusion  DF is a rare benign lesion and can be progressive, invasive, and sometimes recurrent.
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