Effect of Total Intravenous Anesthesia on Wake-up Test in Adolescent Patients Undergoing Scoliosis Surgery

  Objective  To compare the effects of total intravenous anesthesia(TIVA)with propofol-remifentanil and isoflurane-sufentanil on the wake-up test in the scoliosis correction surgery of adolescence.

  Methods  Thirty-two 10-18-year-old patients undergoing elective scoliosis procedures were randomly allocated into two groups:group P(propofol/remifentanil)and group I(isoflurane/sufentanil).The wake-up time and quality during and after the surgery were compared.

  Results  Group P(9.2±3.3 min vs 12.5±6.0 min, P=0.066)required shorter wake-up time during the surgery.The patients in group P had significantly shorter time for the onset of opening eyes(11.6±7.8 min vs 19.7±9.8 min), motion of the feet(12.6±7.9 min vs 22.9±8.7 min), and the extubation(13.4±8.3 min vs 20.4±8.7 min)than those in groug I(P < 0.05).More patients in group I had agitation during the intra-operative wake-up tests(P=0.033).No significant difference was found between the two groups in the incidence of hemodynamic instability or intraoperative awareness.

  Conclusion  The total intravenous anesthesia with propofol and remifentanil can shorten the wake-up time, reduce agitation, and do not induce intra-operative awareness.