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Volume 13 Issue 5
Sep.  2022
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Article Navigation >  Medical Journal of Peking Union Medical College Hospital  > 2022  >  13(5): 864-870
WANG Xiang, SHAO Yajuan, SUN Guibin, ZHOU Na, ZHEN Hongnan, CHEN Jie, ZHAO Lin, BAI Chunmei. Primary Epithelial-myoepithelial Carcinoma of Thymus: First Case Report of the World and Literature Review[J]. Medical Journal of Peking Union Medical College Hospital, 2022, 13(5): 864-870. doi: 10.12290/xhyxzz.2022-0318
Citation: WANG Xiang, SHAO Yajuan, SUN Guibin, ZHOU Na, ZHEN Hongnan, CHEN Jie, ZHAO Lin, BAI Chunmei. Primary Epithelial-myoepithelial Carcinoma of Thymus: First Case Report of the World and Literature Review[J]. Medical Journal of Peking Union Medical College Hospital, 2022, 13(5): 864-870. doi: 10.12290/xhyxzz.2022-0318
shu

Primary Epithelial-myoepithelial Carcinoma of Thymus: First Case Report of the World and Literature Review

doi: 10.12290/xhyxzz.2022-0318
  • 1.

    Department of Medical Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

  • 2.

    Department of Medical Oncology, Beijing Puren Hospital, Beijing 100062, China

  • 3.

    Department of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

  • 4.

    Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

Funds:

National High Level Hospital Clinical Research Funding 2022-PUMCH-A-214

More Information
  • Corresponding author: ZHAO Lin, E-mail: wz20010727@aliyun.com
  • Received Date: 2022-06-09
  • Accepted Date: 2022-07-11
    • Available Online: 2022-07-27
  • Publish Date: 2022-09-30
    Abstract
  •   Objective  To analyze the clinical, imaging and pathological features of patients with epithelial-myoepithelial carcinoma(EMC).  Methods  The data of a patient with primary EMC of the thymus in Peking Union Medical College Hospital was retrospectively analyzed, and the relevant literature was reviewed.  Results  The patient was a middle-aged male diagnosed with primary EMC of the thymus, and he was the first case currently reported at home and abroad. Even though the patient received comprehensive treatments including surgery, chemotherapy, radiotherapy and molecular targeted therapy, he still experienced disease progression, with a survival time of 22 months after surgery.  Conclusions  Primary EMC of the thymus is extremely rare and has atypical clinical manifestations. The diagnosis mainly depends on histopathological examination. Surgery is currently the major treatment and multidisciplinary treatment is very important to prolong the survival time of EMC patients.
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