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Volume 13 Issue 2
Mar.  2022
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Article Navigation >  Medical Journal of Peking Union Medical College Hospital  > 2022  >  13(2): 308-314
LIU Xiaohan, JIN Hongzhong. Risk Factors and Pathogenesis of the Recurrence of Psoriasis[J]. Medical Journal of Peking Union Medical College Hospital, 2022, 13(2): 308-314. doi: 10.12290/xhyxzz.2021-0367
Citation: LIU Xiaohan, JIN Hongzhong. Risk Factors and Pathogenesis of the Recurrence of Psoriasis[J]. Medical Journal of Peking Union Medical College Hospital, 2022, 13(2): 308-314. doi: 10.12290/xhyxzz.2021-0367
shu

Risk Factors and Pathogenesis of the Recurrence of Psoriasis

doi: 10.12290/xhyxzz.2021-0367
  • 1.

    Department of Dermatology, National Clinical Research Center for Dermatologic and Immunologic Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

  • 2.

    State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

Funds:

General Program of National Natural Science Foundation of China 81773331

National Key Research and Development Program of China 2016YFC0901500

CAMS Innovation Fund for Medical Sciences 2021-I2M-1-059

More Information
  • Corresponding author: JIN Hongzhong, E-mail: jinhongzhong@263.net
  • Received Date: 2021-05-01
  • Accepted Date: 2021-07-29
    • Available Online: 2022-01-12
  • Publish Date: 2022-03-30
    Abstract
  • Psoriasis is a kind of chronic recurrent disease, which is easy to recur and protract. It has a severe impact on the life quality of patients. There are multiple factors for the relapse of psoriasis, such as stress, environment, life-style, endocrine and so on. The immunological mechanism of the recurrence of psoriasis is complex. Tissue-resident memory T cells (TRM) may play an important role in the immunological memory of psoriasis. To define the risk factors and the potential pathogenesis of the recurrence of psoriasis can provide basis for the clinical prevention of recurrence and aggravation of psoriasis. To block the function of TRM might open new avenues for preventing the recurrence of psoriasis.
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