Volume 12 Issue 6
Nov.  2021
Turn off MathJax
Article Contents
SUN Juan, LIU Jianzhou, WEN Jin, LI Hanzhong, JI Zhigang, DONG Dexin, YE Zixing, MIAO Qi, TONG Anli, HUANG Yuguang, LONG Yun. Carotid Body Tumor, Cardiac Paraganglioma, Adrenal Pheochromocytoma: A Contest with Hypercatecholamineemia[J]. Medical Journal of Peking Union Medical College Hospital, 2021, 12(6): 1022-1029. doi: 10.12290/xhyxzz.2021-0134
Citation: SUN Juan, LIU Jianzhou, WEN Jin, LI Hanzhong, JI Zhigang, DONG Dexin, YE Zixing, MIAO Qi, TONG Anli, HUANG Yuguang, LONG Yun. Carotid Body Tumor, Cardiac Paraganglioma, Adrenal Pheochromocytoma: A Contest with Hypercatecholamineemia[J]. Medical Journal of Peking Union Medical College Hospital, 2021, 12(6): 1022-1029. doi: 10.12290/xhyxzz.2021-0134

Carotid Body Tumor, Cardiac Paraganglioma, Adrenal Pheochromocytoma: A Contest with Hypercatecholamineemia

doi: 10.12290/xhyxzz.2021-0134
Funds:

Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences 2019XK320027

Project Management Fund for Foreign Cultural and Educational Experts G20190001645

More Information
  • Corresponding author: WEN Jin  Tel: 86-10-69152511, E-mail: wjpumch@163.com
  • Received Date: 2021-01-29
  • Accepted Date: 2021-03-29
  • Available Online: 2021-09-01
  • Publish Date: 2021-11-30
  • This patient was an elderly man with left carotid body tumor, cardiac paraganglioma and right adrenal pheochromocytoma at the same time. It was a rare case with a complex condition, and the diagnosis and treatment were difficult. After two rounds of discussion in the multidisciplinary team, our hospital successively removed the lesions of the heart and the right adrenal, and the patient was discharged smoothly after the operations. The diagnosis and treatment of this patient reflects the significance of the multidisciplinary team on the diagnosis and treatment of difficult diseases.
  • loading
  • [1] 嗜铬细胞瘤和副神经节瘤诊断治疗专家共识(2020版)[J]. 中华内分泌代谢杂志, 2020, 36: 737-750.
    [2] Beard CM, Sheps SG, Kurland LT, et al. Occurrence of pheochromocytoma in Rochester, Minnesota, 1950 through 1979[J]. Mayo Clin Proc, 1983, 58: 802-804. http://www.ncbi.nlm.nih.gov/pubmed/6645626
    [3] McNeil AR, Blok BH, Koelmeyer TD, et al. Phaeochromocytomas discovered during coronial autopsies in Sydney, Melbourne and Auckland[J]. Aust N Z J Med, 2000, 30: 648-652. doi:  10.1111/j.1445-5994.2000.tb04358.x
    [4] Sutton MG, Sheps SG, Lie JT. Prevalence of clinically unsuspected pheochromocytoma. Review of a 50-year autopsy series[J]. Mayo Clin Proc, 1981, 56: 354-360. http://europepmc.org/abstract/med/6453259
    [5] Scoazec JY, Couvelard A, Réseau TENpath. Classification of pancreatic neuroendocrine tumours: Changes made in the 2017 WHO classification of tumours of endocrine organs and perspectives for the future[J]. Ann Pathol, 2017, 37: 444-456. doi:  10.1016/j.annpat.2017.10.003
    [6] Abdelhady K, Durgam S, Orza D, et al. Left Atrial and Carotid Body Paraganglioma[J]. Ann Thorac Surg, 2017, 103: e323-e325. doi:  10.1016/j.athoracsur.2016.09.062
    [7] Erickson D, Kudva YC, Ebersold MJ, et al. Benign paragangliomas: clinical presentation and treatment outcomes in 236 patients[J]. J Clin Endocrinol Metab, 2001, 86: 5210-5216. doi:  10.1210/jcem.86.11.8034
    [8] Al-Harthy M, Al-Harthy S, Al-Otieschan A, et al. Comparison of pheochromocytomas and abdominal and pelvic paragangliomas with head and neck paragangliomas[J]. Endocr Pract, 2009, 15: 194-202. doi:  10.4158/EP.15.3.194
    [9] Eisenhofer G, Tischler AS, de Krijger RR. Diagnostic tests and biomarkers for pheochromocytoma and extra-adrenal paraganglioma: from routine laboratory methods to disease stratification[J]. Endocr Pathol, 2012, 23: 4-14. doi:  10.1007/s12022-011-9188-1
    [10] Kimura N, Watanabe T, Noshiro T, et al. Histological grading of adrenal and extra-adrenal pheochromocytomas and relationship to prognosis: a clinicopathological analysis of 116 adrenal pheochromocytomas and 30 extra-adrenal sympathetic paragangliomas including 38 malignant tumors[J]. Endocr Pathol, 2005, 16: 23-32. doi:  10.1385/EP:16:1:023
    [11] Thompson LD. Pheochromocytoma of the Adrenal gland Scaled Score (PASS) to separate benign from malignant neoplasms: a clinicopathologic and immunophenotypic study of 100 cases[J]. Am J Surg Pathol, 2002, 26: 551-566. doi:  10.1097/00000478-200205000-00002
    [12] Strong VE, Kennedy T, Al-Ahmadie H, et al. Prognostic indicators of malignancy in adrenal pheochromocytomas: clinical, histopathologic, and cell cycle/apoptosis gene expression analysis[J]. Surgery, 2008, 143: 759-768. doi:  10.1016/j.surg.2008.02.007
    [13] de Wailly P, Oragano L, Radé F, et al. Malignant pheochromocytoma: new malignancy criteria[J]. Langenbecks Arch Surg, 2012, 397: 239-246. doi:  10.1007/s00423-011-0850-3
    [14] Agarwal A, Mehrotra PK, Jain M, et al. Size of the tumor and pheochromocytoma of the adrenal gland scaled score (PASS): can they predict malignancy?[J]. World J Surg, 2010, 34: 3022-3028. doi:  10.1007/s00268-010-0744-5
    [15] Chen H, Sippel RS, O'Dorisio MS, et al. The North American Neuroendocrine Tumor Society consensus guideline for the diagnosis and management of neuroendocrine tumors: pheochromocytoma, paraganglioma, and medullary thyroid cancer[J]. Pancreas, 2010, 39: 775-783. doi:  10.1097/MPA.0b013e3181ebb4f0
    [16] Boedeker CC, Neumann HP, Offergeld C, et al. Clinical features of paraganglioma syndromes[J]. Skull Base, 2009, 19: 17-25. doi:  10.1055/s-0028-1103123
    [17] Shen WT, Grogan R, Vriens M, et al. One Hundred Two Patients With Pheochromocytoma Treated at a Single Institution Since the Introduction of Laparoscopic Adrenalectomy[J]. Arch Surg, 2010, 145: 893-897. doi:  10.1001/archsurg.2010.159
    [18] Huang KH, Chung SD, Chen SC, et al. Clinical and pathological data of 10 malignant pheochromocytomas: long-term follow up in a single institute[J]. Int J Urol, 2007, 14: 181-185. doi:  10.1111/j.1442-2042.2007.01687.x
    [19] Jain A, Baracco R, Kapur G. Pheochromocytoma and paraganglioma-an update on diagnosis, evaluation, and management[J]. Pediatr Nephrol, 2020, 35: 581-594. doi:  10.1007/s00467-018-4181-2
    [20] Bholah R, Bunchman TE. Review of Pediatric Pheochromocytoma and Paraganglioma[J]. Front Pediatr, 2017, 5: 155. doi:  10.3389/fped.2017.00155
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Figures(3)  / Tables(1)

    Article Metrics

    Article views (442) PDF downloads(125) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return