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中国耳念珠菌临床感染现状

徐英春,  黄晶晶,  肖盟,  陈新飞,  宁雅婷,  范欣,  杨洋,  冯佳佳,  林丽开

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文章导航 > 协和医学杂志  > 2019 >  10(5): 442-445
徐英春, 黄晶晶, 肖盟, 陈新飞, 宁雅婷, 范欣, 杨洋, 冯佳佳, 林丽开. 中国耳念珠菌临床感染现状[J]. 协和医学杂志, 2019, 10(5): 442-445. doi: 10.3969/j.issn.1674-9081.2019.05.003
引用本文: 徐英春, 黄晶晶, 肖盟, 陈新飞, 宁雅婷, 范欣, 杨洋, 冯佳佳, 林丽开. 中国耳念珠菌临床感染现状[J]. 协和医学杂志, 2019, 10(5): 442-445. doi: 10.3969/j.issn.1674-9081.2019.05.003
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Ying-chun XU, Jing-jing HUANG, Meng XIAO, Xin-fei CHEN, Ya-ting NING, Xin FAN, Yang YANG, Jia-jia FENG, Li-kai LIN. Current Status of Clinical Infection of Candida Auris in China[J]. Medical Journal of Peking Union Medical College Hospital, 2019, 10(5): 442-445. doi: 10.3969/j.issn.1674-9081.2019.05.003
Citation: Ying-chun XU, Jing-jing HUANG, Meng XIAO, Xin-fei CHEN, Ya-ting NING, Xin FAN, Yang YANG, Jia-jia FENG, Li-kai LIN. Current Status of Clinical Infection of Candida Auris in China[J]. Medical Journal of Peking Union Medical College Hospital, 2019, 10(5): 442-445. doi: 10.3969/j.issn.1674-9081.2019.05.003
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中国耳念珠菌临床感染现状

doi: 10.3969/j.issn.1674-9081.2019.05.003
  • 1.

    中国医学科学院 北京协和医学院 北京协和医院检验科, 北京 100730

  • 2.

    侵袭性真菌病机制研究与精准诊断北京市重点实验室, 北京 100730

  • 3.

    武汉大学医院管理研究所, 武汉 430071

基金项目: 

"艾滋病和病毒性肝炎等重大传染病防治"国家科技重大专项 2018ZX10712001

"精准医学研究"国家重点研发计划 2016YFC0901500

详细信息
    通讯作者:

    林丽开 电话:027-67813059, E-mail:1875278110@qq.com

  • 中图分类号: R519;R446

Current Status of Clinical Infection of Candida Auris in China

  • 1.

    Department of Clinical Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

  • 2.

    Beijing Key Laboratory for Mechanisms Research and Precision Diagnosis of Invasive Fungal Diseases, Beijing 100730, China

  • 3.

    Hospital Management Institution, Wuhan University, Wuhan 430071, China

More Information

    摘要
  • 摘要: 耳念珠菌是近年新发现的念珠菌种, 在部分国家尤其是美国呈现耐药性及院内感染暴发态势。"超级病原"及其引申出来的"超级真菌"在真菌领域罕被提及, 但近来"耳念珠菌是超级真菌"的言论却在互联网上广为流传。现有报道及其流行病学监测数据显示, 中国耳念珠菌临床发生发展情况与美国不同, 其所引发的感染仍属个案, 且药物敏感度高, 致病性不强于常见非-白念珠菌。因此, 公众无需过度解读, 以致产生不必要的恐慌。
    Abstract: Candida auris is an emerging pathogen in recent years that has developed resistance and caused nosocomial outbreaks in some countries especially in the United States. The term "super fungi" derived from "superbug", and it is rarely mentioned in the field of fungi. However, recently the articles with the definition that "Candida auris is a super fungi" are widely circulated on the internet. The situation of Candida auris in China differs from that in the United States according to existing reports and epidemiological surveillance data. The infection caused by it is still sporadic, and isolations of Candida auris are active to antifungal agents. Meanwhile, its pathogenicity is not stronger than the common non-albican Candida species. Therefore, the public should avoid excessive interpretation of the articles with unnecessary panic.
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    • 参考文献(18)
  • [1] WHO. Antimicrobial resistance: no action today, no cure tomorrow[EB/OL]. https://www.who.int/world-health-day/2011/en/.
    [2] 国家卫生健康委员会.国家卫生健康委办公厅关于持续做好抗菌药物临床应用管理工作的通知[EB/OL]. http://www.nhc.gov.cn/yzygj/s7659/201903/1d487eb7b7c74abc9fcb104f8b0905f2.shtml.
    [3] Satoh K, Makimura K, Hasumi Y, et al. Candida auris sp. nov., a novel ascomycetous yeast isolated from the external ear canal of an inpatient in a Japanese hospital[J]. Microbiol Immunol, 2009, 53:41-44. doi:  10.1111/j.1348-0421.2008.00083.x
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    [5] US CDC. Tracking Candida auris [EB/OL]. https://www.cdc.gov/fungal/candida-auris/tracking-c-auris.html.
    [6] Lockhart SR, Etienne KA, Vallabhaneni S, et al. Simultaneous Emergence of Multidrug-Resistant Candida auris on 3 Continents Confirmed by Whole-Genome Sequencing and Epidemiological Analyses[J]. Clin Infect Dis, 2017, 64:134-140. doi:  10.1093/cid/ciw691
    [7] Clancy CJ, Nguyen MH. Emergence of Candida auris:An International Call to Arms[J]. Clin Infect Dis, 2017, 64:141-143. doi:  10.1093/cid/ciw696
    [8] Eyre DW, Sheppard AE, Madder H, et al. A Candida auris Outbreak and Its Control in an Intensive Care Setting[J]. N Engl J Med, 2018, 379:1322-1331. doi:  10.1056/NEJMoa1714373
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    [10] Chen Y, Zhao J, Han L, et al. Emergency of fungemia cases caused by fluconazole-resistant Candida auris in Beijing, China[J]. J Infect, 2018, 77:561-571. http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=506e946cddd09b4180b73fbd11b6105b
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    [13] 郭晶.构建合理用药"金标准":北京协和医院开展临床重要致病性真菌新型诊断技术及全国多中心监测[J].协和医学杂志, 2013, 4:244. http://www.cnki.com.cn/Article/CJFDTotal-XHYX201303009.htm
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    [16] Hou X, Xiao M, Chen SC, et al. Identification and Antifungal Susceptibility Profiles of Candida haemulonii Species Complex Clinical Isolates from a Multicenter Study in China[J]. J Clin Microbiol, 2016, 54:2676-2680. doi:  10.1128/JCM.01492-16
    [17] Adams E, Quinn M, Tsay S, et al. Candida auris in Healthcare Facilities, New York, USA, 2013-2017[J]. Emerg Infect Dis, 2018, 24:1816-1824. doi:  10.3201/eid2410.180649
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出版历程
  • 收稿日期:  2019-04-25
  • 刊出日期:  2019-09-30

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