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乳糜泻诊断技术进展

李融融,  严婧文,  柳思华,  吴东

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文章导航 > 协和医学杂志  > 2020 >  11(2): 174-180
李融融, 严婧文, 柳思华, 吴东. 乳糜泻诊断技术进展[J]. 协和医学杂志, 2020, 11(2): 174-180. doi: 10.3969/j.issn.1674-9081.20180395
引用本文: 李融融, 严婧文, 柳思华, 吴东. 乳糜泻诊断技术进展[J]. 协和医学杂志, 2020, 11(2): 174-180. doi: 10.3969/j.issn.1674-9081.20180395
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Rong-rong LI, Jing-wen YAN, Si-hua LIU, Dong WU. Progress in Diagnostic Techniques for Celiac Disease[J]. Medical Journal of Peking Union Medical College Hospital, 2020, 11(2): 174-180. doi: 10.3969/j.issn.1674-9081.20180395
Citation: Rong-rong LI, Jing-wen YAN, Si-hua LIU, Dong WU. Progress in Diagnostic Techniques for Celiac Disease[J]. Medical Journal of Peking Union Medical College Hospital, 2020, 11(2): 174-180. doi: 10.3969/j.issn.1674-9081.20180395
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乳糜泻诊断技术进展

doi: 10.3969/j.issn.1674-9081.20180395
  • 1.

    中国医学科学院 北京协和医学院 北京协和医院 临床营养科, 北京 100730

  • 2.

    中国医学科学院 北京协和医学院临床医学(八年制), 北京 100730

  • 3.

    中国医学科学院 北京协和医学院 北京协和医院 消化内科, 北京 100730

基金项目: 

北京协和医学院研究生教育教学改革项目 100232017

北京协和医学院中央高校基本科研业务费项目青年教师项目 3332018014

详细信息
    通讯作者:

    吴东 电话:010-69155017, E-mail:wudong@pumch.cn

  • 中图分类号: R574

Progress in Diagnostic Techniques for Celiac Disease

  • 1.

    Department of Clinical Nutrition, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

  • 2.

    Clinical Medical School, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

  • 3.

    Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

More Information
    Corresponding author: WU Dong Tel: 86-10-69155017, E-mail:wudong@pumch.cn

    摘要
  • 摘要: 乳糜泻是一种在遗传易感人群中因摄入含麦胶食物而引起的慢性自身免疫性肠道炎症。目前, 随着检测技术的迅速发展及人们对于乳糜泻的认识加深, 血清抗体、遗传风险以及小肠组织病理已联合应用于诊断乳糜泻。本文回顾乳糜泻诊断技术的进展及争议, 以期提高读者对于乳糜泻诊断的认识。
    Abstract: Celiac disease is an immune-mediated intestinal disorder characterized by chronic inflammation of the small intestine, triggered and maintained by exposure to gluten in the diet. The rapid development of technology and a better understanding of the mechanism of celiac disease lead to combining the application of new serologic diagnostic tests, certain genetic markers, and histopathologic evaluation to aid the diagnosis of celiac disease. We reviewed the recent progress and debate of the diagnostic techniques for celiac disease.
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  • 图  1  乳糜泻诊断流程

    anti-tTG：抗组织转谷氨酰胺酶抗体；anti-DGP：抗脱酰氨基麦胶蛋白肽；EMA：抗肌内膜抗体；HLA：人类白细胞抗原

    下载: 全尺寸图片 幻灯片
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  • 收稿日期:  2018-09-03
  • 刊出日期:  2020-03-30

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