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图 1 经济危机中的美国群众[4]
图 2 华法林的分子结构[8]
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[1] Pirmohamed M. Warfarin: almost 60 years old and still causing problems [J]. Br J Clin Pharmacol, 2006, 62: 509-511. doi: 10.1111/j.1365-2125.2006.02806.x [2] Patel MR, Mahaffey KW, Garg J, et al. Rivaroxaban versus warfarin in nonvalvular atrial fibrillation [J]. N Engl J Med, 2011, 365: 883-891. doi: 10.1056/NEJMoa1009638 [3] Schofield FW. Damaged sweet clover: the cause of a new disease in cattle stimulating hemorrhagic septicaemia and blackleg [J]. J Am Vet Med Assoc, 1924, 64: 553-575. [4] https://commons.wikimedia.org/wiki/File:Volunteers_of_America_Soup_Kitchen_WDC.gif?uselang=zh-cn. [5] Burris RH. Karl paul link[M]//Burris RH. Biographical Memoirs V.64. Washington DC:National Academy Press, 1994:175-195. [6] Wardrop D, Keeling D. The story of the discovery of heparin and warfarin [J]. Br J Haematol, 2008, 141: 757-763. doi: 10.1111/j.1365-2141.2008.07119.x [7] Petit DW, Berne CJ. Medical progress: DICUMAROL [J]. Calif Med, 1947, 67: 40-44. [8] https://commons.wikimedia.org/wiki/Category:Warfarin#/media/File:Warfarin_ball-and-stick_model.png.