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维生素D及其类似物临床应用共识

中华医学会骨质疏松和骨矿盐疾病分会

中华医学会骨质疏松和骨矿盐疾病分会. 维生素D及其类似物临床应用共识[J]. 协和医学杂志, 2018, 9(2): 127-143. doi: 10.3969/j.issn.1674-9081.2018.02.007
引用本文: 中华医学会骨质疏松和骨矿盐疾病分会. 维生素D及其类似物临床应用共识[J]. 协和医学杂志, 2018, 9(2): 127-143. doi: 10.3969/j.issn.1674-9081.2018.02.007

维生素D及其类似物临床应用共识

doi: 10.3969/j.issn.1674-9081.2018.02.007
详细信息
    通讯作者:

    夏维波  电话:010-69155112, Email:xiaweibo8301@163.com

  • 中图分类号: R58;R451

More Information
  • 图  1  维生素D的化学结构

    图  2  维生素D的代谢途径

    表  1  建议筛查血25OHD水平的人群

    建议筛查人群
    特殊人群 妊娠和哺乳期女性
    有跌倒史和/或有非创伤性骨折史的老年人
    缺乏日照的人群(室内工作、夜间工作等)
    肥胖儿童和成人(BMI≥30 kg/m2)
    接受减重手术的人群
    疾病状态 佝偻病
    骨软化症
    骨质疏松症
    甲状旁腺功能亢进症
    慢性肾脏病
    肝功能衰竭
    小肠吸收不良综合征
    急/慢性腹泻、脂肪泻
    胰腺囊性纤维化
    炎性反应性肠病(克罗恩病、溃疡性结肠炎)
    放射性肠炎
    淋巴瘤
    形成肉芽肿的疾病
      结节病
      结核病
      艾滋病
      组织胞浆菌病
      球孢子菌病
      慢性铍中毒
    某些药物 抗癫痫药物:苯妥英钠、苯巴比妥等
    糖皮质激素:泼尼松等
    抗结核药物:利福平等
    唑类抗真菌药物:酮康唑等
    某些调脂药物:考来烯胺(消胆胺)等
    BMI:体质量指数
    下载: 导出CSV

    表  2  维生素D缺乏高危人群维生素D补充推荐

    年龄 建议补充剂量(IU/d) 年龄 可耐受摄入上限(IU/d)
    0~1岁 400~1000 0~6个月 1000
    >1~18岁 600~1000 >6个月~1岁 1500
    >18~50岁 1500~2000 >1~3岁 2500
    >50~70岁 1600~2000 >3~8岁 3000
    >70岁 1600~2000 >8岁 4000
    下载: 导出CSV
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