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关键词:
- SAPHO综合征 /
- 正电子发射计算机断层显像 /
- 放射影像学
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图 1 颈椎(2011-02-22)及腰椎(2011-09-23)MRI(T2相)示第6颈椎椎体(A, 橙色箭头)、第1腰椎椎体下缘和第2腰椎椎体上缘(B, 红色箭头)高信号(长T2), 第1腰椎椎体骨质破坏
图 2 PET/CT冠状位、矢状位和水平位显像(2011- 09-13)
A.全身PET示第1胸肋关节(黄色箭头)、第6颈椎椎体(白色箭头)和第1、2腰椎椎体高代谢灶(红色箭头); B. PET示第6颈椎椎体高代谢灶, CT示第6颈椎椎体骨质溶解和破坏; C.PET示第1腰椎椎体前下缘及第2腰椎椎体上缘高代谢灶上:CT相; 下:PET相
图 3 PET/CT横断面显像(2011- 09-13)
上:CT示相应骨质破坏/溶解(A、C)或骨质硬化(B、C); 下:PET示第6颈椎椎体(A)、左侧第1胸肋关节(B)和第1腰椎椎体(C)高代谢灶
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[1] Chamot AM, Benhamou CL, Kahn MF, et al. Acne-pustulosis-hyperostosis-osteitis syndrome. Results of a national survey 85 cases[J]. Rev Rhum Mal Osteoartic, 1987, 54:187-196. http://europepmc.org/abstract/MED/2954204 [2] Colina M, Govoni M, Orzincolo C, et al. Clinical and radiologic evolution of synovitis, acne, pustulosis, hyperostosis, and osteitis syndrome:a single center study of a cohort of 71 subjects[J]. Arthritis Care Res, 2009, 61:813-821. doi: 10.1002/art.24540 [3] Magrey M, Khan MA. New insights into synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome[J]. Curr Rheumatol Rep, 2009, 11:329-333. doi: 10.1007/s11926-009-0047-8 [4] Salles M, Olive A, Perez-Andres R, et al. The SAPHO syndrome:a clinical and imaging study[J]. Clin Rheumatol, 2011, 30:245-249. doi: 10.1007/s10067-010-1560-x [5] Earwaker JW, Cotten A. SAPHO:syndrome or concept? Ima-ging findings[J]. Skeletal Radiol, 2003, 32:311-327. doi: 10.1007/s00256-003-0629-x [6] Pichler R, Weiglein K, Schmekal B, et al. Bone scintigraphy using Tc-99m DPD and F18-FDG in a patient with SAPHO syndrome[J]. Scand J Rheumatol, 2003, 32:58-60. doi: 10.1080/03009740310000436 [7] Patel CN, Smith JT, Rankine JJ, et al. F-18 FDG PET/CT can help differentiate SAPHO syndrome from suspected metastatic bone disease[J]. Clin Nucl Med, 2009, 34:254-257. doi: 10.1097/RLU.0b013e31819a205c [8] Inoue K, Yamaguchi T, Ozawa H, et al. Diagnosing active inflammation in the SAPHO syndrome using 18FDG-PET/CT in suspected metastatic vertebral bone tumors[J]. Ann Nucl Med, 2007, 21:477-480. doi: 10.1007/s12149-007-0051-x -
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