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表 1 恶性肿瘤患者血栓与止血相关指标实验室检测
1. TEG $ \bullet $对凝血纤溶全过程和血小板功能进行全面评估,鉴别出凝血及纤溶亢进原因 $ \bullet $指导输血及用药,监测药物疗效 2.血小板数目与功能检测 $ \bullet $血小板计数、形态学检查 $ \bullet $PAdT、PAgT、血小板膜糖蛋白测定、β-TG、PF4、P-选择素 $ \bullet $TEG platelet mapping 3.凝血纤溶系统活化标志物 $ \bullet $凝血因子活化标志物: F1 + 2、FPA、TF、SFMC、凝血因子水平及活性 $ \bullet $抗凝系统活化标志物: AT-Ⅲ:A、PC:A、PS:A、TAT、TEPI $ \bullet $纤溶系统活化标志物: t-PA、u-PA、Fbg、DD、FDP、PAP 4.血液流变学检查 5.内皮损伤标志物 $ \bullet $TM、vWF、ET-1 TEG:血栓弹力图; PAdT:血小板黏附试验; PAgT:血小板聚集试验; β-TG: β-血小板球蛋白; PF4 :血小板因子4; F1 + 2:纤维蛋白原片段1 + 2; FPA:纤维蛋白肽A; TF:组织因子; SFMC:可溶性纤维蛋白单体复合物; AT-Ⅲ:A:抗凝血酶-Ⅲ活性; PC:A:蛋白C活性; PS:A:蛋白S活性; TAT:凝血酶-抗凝血酶; TEPI:组织因子途径抑制物; t-PA:组织型纤溶酶原活化剂; u-PA:尿激酶型纤溶酶原活化物; Fbg:纤维蛋白原; DD: D二聚体; FDP:纤维蛋白原降解产物; PAP:纤溶酶-α2-抗纤溶酶复合物; TM:血栓调节蛋白; vWF:血管性血友病因子; ET-1:内皮素-1 -
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