Values of Red Green Blue and Ultraviolet Images in Diagnosis and Treatment of Vitiligo in Patients with Head or Neck Leukoplakia
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摘要:
目的 探讨头颈部白斑患者红绿蓝(red green blue, RGB)光和紫外线(ultraviolet, UV)光图像在白癜风诊断、治疗及疗效评价中的价值。 方法 应用皮肤分析仪对608例头颈部白斑患者进行RGB光和UV光拍照, 定性分析同一患者头颈部白斑在RGB光和UV光下白癜风病变边界的区别。 结果 白癜风皮损在UV光下表现为界限清楚的亮白色荧光。608例头颈部白斑患者中, 通过RGB和UV图像确诊为白癜风281例(46.2%), 除外286例(47.0%), 不能明确诊断41例(6.7%)。部分黏膜和头皮部位受累的白癜风因颜色浅, 诊断困难, UV图像可明确诊断。肉眼不能明确白癜风皮损界限时, UV图像可明确受累范围, 指导治疗。对于疗效的评价, UV图像可更有效地确定复色范围, 并提示治疗后肉眼不可见皮损。 结论 头颈部白斑患者RGB和UV图像分析可用于诊断或除外白癜风, 特别是肉眼难于鉴别的皮损; 能有效地指导治疗和进行疗效评价, 更有效地确定复色范围。 Abstract:Objective To investigate the role of red green blue (RGB) and ultraviolet (UV) images in the diagnosis and treatment of vitiligo in patients with head or neck leukoplakia. Methods RGB and UV photos of 608 patients with head or neck leukoplakia were taken using a skin analyzer. The difference of the borders of vitiligo between the RGB and UV images of these patients was qualitatively analyzed. Results Vitiligo lesions under UV were bright fluorescence with clear borders. Of these 608 patients with head or neck leukoplakia, vitiligo was finally confirmed in 281 patients (46.2%) and excluded in 286 patients (47.0%), although 41 (6.7%) remained uncertain. Vitiligo lesions in mucosa and scalp were not obvious, but they could be identified with UV. For borders of vitiligo that were not clear in RGB images, they could be identified in UV images. During the treatment, UV images are more effective in defining the repigmented area and indicating the lesions not visible to the naked eye. Conclusions Combined RGB and UV imaging is effective means for the diagnosis of vitiligo, especially for lesions in mucosa and scalp. They can also provide useful information during the decision-making and evaluation of treatment. -
Key words:
- head or neck leukoplakia /
- vitiligo /
- red green blue light /
- ultraviolet light
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图 2 除外白癜风者RGB和UV图像
儿童除外白癜风者RGB (A)和UV (B)图像,UV图像示界限欠清的弱白色荧光; 青年除外白癜风者RGB (C)和UV (D)图像,UV图像示界限较清晰的暗白色荧光; 老年除外白癜风者RGB (E)和UV (F)图像,UV图像示界限欠清的弱白色荧光RGB、UV:同图 1
图 3 白癜风患者治疗前(A、B)、308 nm准分子激光治疗2个月(C、D)、6个月(E、F)的RGB和UV图像显示皮损改善比较
RGB、UV:同图 1
图 4 口唇受累白癜风患者RGB (A)和UV (B)图像,UV光下表现为界限清晰的亮白色荧光
RGB、UV:同图 1
图 5 头皮受累白癜风患者RGB (A)和UV (B)图像,UV光下表现为界限清晰的亮白色荧光
RGB、UV:同图 1
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