作者投稿
专家审稿
编辑办公
邮件订阅
RSS
Dual-wavelength Laser with 595 nm and 1064 nm Combination for Resistant Port-wine Stains
-
摘要:
目的 评价双波长595 nm和1064 nm激光器治疗难治性鲜红斑痣的疗效和安全性。 方法 回顾性分析北京协和医院皮肤科激光中心2009年1月至2011年12月间采用双波长595 nm和1064 nm激光器治疗16例对传统脉冲染料激光治疗抵抗的难治性鲜红斑痣患者的资料, 评价其疗效和安全性。 结果 16例患者中2例痊愈, 6例显效, 6例有效, 2例无效。3例患者出现水疱, 2例出现瘢痕, 无其他不良反应发生。 结论 双波长595 nm和1064 nm激光器对难治性鲜红斑痣疗效显著, 不良反应较少。 Abstract:Objective To evaluate the effectiveness and safety of dual-wavelength laser in treating the resistant port-wine stains (PWS). Methods Sixteen patients with single wavelength pulsed dye laser (PDL)-resistant PWS were subsequently treated with a dual-wavelength laser (595 nm and 1064 nm combination) in our department from January 2009 to December 2011. Their outcomes were recorded and retrospectively analyzed. Results Of the 16 patients, 2 were cured, 6 markedly effective, 6 effective, and 2 ineffective. Vesiculation and scarring were seen in 3 and 2 patients, respectively, whereas no other adverse effects were reported. Conclusion The novel dual-wavelength (595 nm and 1064 nm) laser is an effective and safe device for PWS that is resistant to PDL therapy alone. -
图 1 鲜红斑痣双波长激光治疗前后对比
A.病例14脉冲染料激光治疗5次后无效，双波长激光治疗前; B.病例14双波长激光治疗6次后痊愈; C.病例15脉冲染料激光治疗6次后无效，双波长激光治疗前; D.病例15双波长激光治疗3次后显效
表 1 16例难治性鲜红斑痣患者的基本情况及激光治疗效果
病例 年龄(岁) 性别 部位 脉冲染料激光次数 双波长激光次数 疗效 不良反应 1 36 女 面部 5 2 有效 无 2 14 女 面部 6 1 有效 无 3 9 女 面部 5 2 无效 无 4 23 女 面部 6 5 显效 水疱 5 13 男 面部 6 1 有效 无 6 2 男 面部 7 1 无效 局部瘢痕 7 20 女 小腿 6 2 显效 无 8 2 女 面颈部 7 2 有效 无 9 13 女 面部 5 7 痊愈 水疱 10 8 男 面部 5 6 显效 无 11 33 女 面部 6 3 有效 无 12 4 女 面颈部 5 4 有效 水疱 13 33 女 小腿 6 4 显效 无 14 21 女 面部 5 6 痊愈 无 15 14 男 面部 6 3 显效 无 16 12 女 面部 5 6 显效 轻度瘢痕 
下载: 导出CSV
-
[1] Lorenz S, Maier C, Segerer H, et al. Skin changes in newborn infants in the first 5 days of life[J]. Hautarzt, 2000, 51:396-400. doi: 10.1007/s001050051140 [2] Jacobs AH, Walton RG. The incidence of birthmarks in the neonate[J]. Pediatrics, 1976, 58:218-222. http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=WK_LWW2017052520385511 [3] Faurschou A, Olesen AB, Leonardi-Bee J, et al. Lasers or light sources for treating port-wine stains[J]. Cochrane Database Syst Rev, 2011, (11):CD007152. doi: 10.1002/14651858.CD007152.pub2/pdf [4] Shah S, Alster TS. Laser treatment of dark skin:an updated review[J]. Am J Clin Dermatol, 2010, 11:389-397. doi: 10.2165/11538940-000000000-00000 [5] Viator JA, Au G, Paltauf G, et al. Clinical testing of a photoacoustic probe for port wine stain depth determination[J]. Lasers Surg Med, 2002, 30:141-148. doi: 10.1002/lsm.10015 [6] Izikson L, Nelson JS, Anderson RR. Treatment of hypertrophic and resistant port wine stains with a 755nm laser:a case series of 20 patients[J]. Lasers Surg Med, 2009, 41:427-432. doi: 10.1002/lsm.20793 [7] Alster TS, Tanzi EL. Combined 595-nm and 1, 064-nm laser irradiation of recalcitrant and hypertrophic port-wine stains in children and adults[J]. Dermatol Surg, 2009, 35:914-919. doi: 10.1111/j.1524-4725.2009.01155.x [8] 左亚刚, 王家璧, 姜国调, 等. 585nm脉冲染料激光治疗鲜红斑痣2317例回顾性分析[J].中国医学科学院学报, 2006, 28:206-209. http://www.cnki.com.cn/Article/CJFDTotal-ZYKX200602019.htm [9] Whang KK, Byun JY, Kim SH. A dual-wavelength approach with 585nm pulsed-dye laser and 800nm diode laser for treatment-resistant port-wine stains[J]. Clin Exp Dermatol, 2009, 34:e436-e437. doi: 10.1111/j.1365-2230.2009.03454.x [10] Edstrom DW, Ros AM. The treatment of port-wine stains with the pulsed dye laser at 600nm[J]. Br J Dermatol, 1997, 136:360-363. doi: 10.1046/j.1365-2133.1997.d01-1200.x [11] Peters MA, van Drooge AM, Wolkerstorfer A, et al. Double pass 595 nm pulsed dye laser at a 6 minute interval for the treatment of port-wine stains is not more effective than single pass[J]. Lasers Surg Med, 2012, 44:199-204. doi: 10.1002/lsm.22011 [12] Frohm Nilsson M, Passian S, Wiegleb Edstrom D. Comparison of two dye lasers in the treatment of port-wine stains[J]. Clin Exp Dermatol, 2010, 35:126-130. doi: 10.1111/j.1365-2230.2009.03399.x [13] Yang MU, Yaroslavsky AN, Farinelli WA, et al. Longpulsed neodymium:yttrium-almuminum-garnet laser treatment of deep cutaneous vascular lesions[J]. Dermatol Surg, 2003, 29:35-42. -
点击查看大图
图(1) / 表(1)
计量
- 文章访问数: 203
- HTML全文浏览量: 56
- PDF下载量: 5
- 被引次数: 0
