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摘要: 口腔健康与全身健康息息相关。常见的口腔慢性疾病,如牙周炎和根尖周炎,一方面可影响牙槽骨和牙龈等口腔软硬组织健康,另一方面还可能引起全身慢性低度炎症、氧化应激水平升高和菌群失调等全身症状,而这些全身健康状况的改变可加剧肥胖进展。因此,通过口腔主动健康干预,如保持良好的口腔卫生习惯、改变饮食结构、主动寻求口腔检查等,不仅可有效预防和治疗口腔炎症性疾病,还可能通过改善全身健康状态从而解决肥胖问题。本文深入探讨口腔炎症性疾病对肥胖的影响及其内在机制,定义了“口腔主动健康”概念,并系统总结其对口腔炎症性疾病的防治作用,讨论通过口腔主动健康策略改善肥胖的可能性。Abstract: Oral health is closely related to systemic health. Common chronic oral diseases, periodontitis and periapical inflammation for example, not only affect the health of oral soft and hard tissues including the alveolar bone and gums, but may also cause changes in systemic conditions such as chronic low-grade inflammation, elevated oxidative stress levels, and dysbiosis of the microbiota. These changes in systemic health can exacerbate the progression of obesity. Therefore, through proactive oral health interventions such as maintaining good oral hygiene habits, modifying dietary structures, and undergoing oral examinations, it is possible to effectively prevent and alleviate inflammatory oral diseases, and actively intervene in obesity. This article delves into the impact of inflammatory oral diseases on obesity and their underlying mechanisms, defines the concept of "oral proactive healthcare", and systematically summarizes their preventive and therapeutic effects on inflammatory oral diseases, thereby demonstrating the potential of improving obesity through proactive oral health strategies.作者贡献:崔靖、杜函泽、翟文昊、温琳琳、黄蕾负责文献收集整理和论文撰写;陈适、李道伟负责论文修订;潘慧负责论文设计和指导。利益冲突:所有作者均声明不存在利益冲突
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