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摘要: 乳腺癌作为女性恶性肿瘤中最常见的肿瘤之一, 多向骨、肝、肺等部位发生转移, 而乳腺癌胃转移的病例较为少见, 与原发性胃癌的鉴别亦是临床工作中的一大难点。本文报道1例乳腺癌胃转移患者, 根据该患者的免疫组化结果, 结合病史, 最终诊断为起源于乳腺小叶癌的转移性浸润性胃腺癌, 行内镜下黏膜剥离术后给予氟维司群注射液联合阿贝西利内分泌治疗, 患者预后良好。本文总结该患者的临床表现、诊断及治疗经过, 以期为乳腺癌胃转移的临床诊疗提供参考。Abstract: Breast cancer, one of the most common female malignant tumours, mostly metastasizes to the bone, liver and lung. The case of gastric metastasis of breast cancer is relatively rare, and the differentiation of breast cancer from primary gastric cancer is also a major difficulty in clinical practice. In this paper, we report a rare case of gastric metastasis from breast cancer, which was diagnosed as metastatic invasive gastric adenocarcinoma originating from lobular carcinoma of the breast according to the immunohistochemical results of the patient, combined with the patient's medical history. The patient was given fulvestrant injection combined with abecycline for endocrine therapy against tumour after endoscopic mucosal dissection, and the prognosis was good. The clinical manifestations, diagnosis and treatment of this disease are discussed through relevant literature review, with the aim of providing reference for the clinical diagnosis and treatment of gastric metastasis of breast cancer.
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Key words:
- breast cancer /
- gastric metastasis /
- differential diagnosis /
- rare disease
作者贡献：杨琳负责资料收集、论文撰写；苏莎莎负责论文审校及修订。利益冲突：所有作者均声明不存在利益冲突注：本研究发表已获得患者知情同意。 -
图 2 患者胃窦、胃角免疫组化染色结果(×20)
A. Ki-67指数(+)；B.ER(+)；C.PR(-)；D.C-erbB-2(+)；E.CDX-2(-)；F.GATA-3(+)
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