胃内微生态在胃癌发生发展过程中的作用机制

田梦; 武国兵; 杨锦; 欧阳晶; 常虹; 刘敏; 郑亚; 陈兆峰

doi:10.12290/xhyxzz.2022-0593

胃内微生态在胃癌发生发展过程中的作用机制

doi: 10.12290/xhyxzz.2022-0593

田梦^{1, 2, 3},
武国兵^{1, 2, 3},
杨锦^{1, 2, 3},
欧阳晶^{1, 2, 3},
常虹^{1, 2, 3},
刘敏^{2, 3},
郑亚^{2, 3},
陈兆峰^{2, 3, ,}

1.
兰州大学第一临床医学院，兰州 730000
2.
兰州大学第一医院消化内科，兰州 730000
3.
兰州大学第一医院甘肃省胃肠病重点实验室，兰州 730000

基金项目:

国家自然科学基金 81960430

兰州市科技计划 2021-1-111

兰州大学第一医院院内基金 ldyyyn2021-6

详细信息

通讯作者:
陈兆峰, E-mail: zhfchen@lzu.edu.cn

中图分类号: R735.2;R-1;R37
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- 文章访问数: 246
- HTML全文浏览量: 57
- PDF下载量: 77
- 被引次数: 0
出版历程
- 收稿日期: 2022-10-12
- 录用日期: 2023-02-09
- 网络出版日期: 2023-04-12
- 刊出日期: 2023-05-30

Research Progress on the Mechanism of Gastric Microecology in the Development of Gastric Cancer

TIAN Meng^{1, 2, 3},
WU Guobing^{1, 2, 3},
YANG Jin^{1, 2, 3},
OUYANG Jing^{1, 2, 3},
CHANG Hong^{1, 2, 3},
LIU Min^{2, 3},
ZHENG Ya^{2, 3},
CHEN Zhaofeng^{2, 3
, ,}

1.
The First Clinical Medical School, Lanzhou University, Lanzhou 730000, China
2.
Department of Gastroenterology, the First Hospital of Lanzhou University, Lanzhou 730000, China
3.
Key Laboratory of Gastrointestinal Diseases of Gansu Province, the First Hospital of Lanzhou University, Lanzhou 730000, China

Funds:

National Natural Science Foundation of China 81960430

Lanzhou Science and Technology Plan Project 2021-1-111

The First Hospital of Lanzhou University Hospital Fund ldyyyn2021-6

More Information

Corresponding author: CHEN Zhaofeng, E-mail: zhfchen@lzu.edu.cn

摘要

摘要: 微生态已被证明与消化系统疾病密切相关，而关乎胃内微生态的研究大多以幽门螺杆菌为重点。随着微阵列及基因检测技术的发展，除幽门螺杆菌外，越来越多的菌属如放线菌、厚壁菌、梭状菌等被发现，且被证明与胃癌的发生发展过程密切相关。本文通过回顾相关文献，对胃内微生态在胃癌发生发展过程中的作用及可能机制展开综述，以期为临床诊疗提供参考。
- 胃内微生态 /
- 幽门螺杆菌 /
- 胃癌 /
- 作用机制
Abstract: Microecology has been shown to be closely related to digestive diseases, and most of the research on gastric microecology has focused on Helicobacter pylori. With the development of microarray and gene detection technology, in addition to Helicobacter pylori, more and more bacteria genera have been discovered, such as Actinomyces, Firmicute and Clostridium. These bacteria genera and their abundance changes have also been proved to be closely related to the occurrence and development of gastric cancer. In this paper, the role and possible mechanism of gastric microecology in the occurrence and development of gastric cancer are reviewed, with the hope of providing reference for clinical diagnosis and treatment.
- intragastric microecology /
- Helicobacter pylori /
- gastric cancer /
- mechanism of action
注释:

作者贡献：田梦、武国兵、杨锦、欧阳晶、常虹负责文献检索和论文撰写；刘敏、郑亚、陈兆峰负责论文修订。

利益冲突：所有作者均声明不存在利益冲突

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参考文献(40)

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胃内微生态在胃癌发生发展过程中的作用机制

doi: 10.12290/xhyxzz.2022-0593

通讯作者:
陈兆峰, E-mail: zhfchen@lzu.edu.cn

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Research Progress on the Mechanism of Gastric Microecology in the Development of Gastric Cancer

Corresponding author: CHEN Zhaofeng, E-mail: zhfchen@lzu.edu.cn

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留言板

胃内微生态在胃癌发生发展过程中的作用机制

doi: 10.12290/xhyxzz.2022-0593

通讯作者: 陈兆峰, E-mail: zhfchen@lzu.edu.cn

计量

出版历程

Research Progress on the Mechanism of Gastric Microecology in the Development of Gastric Cancer

Corresponding author: CHEN Zhaofeng, E-mail: zhfchen@lzu.edu.cn

计量

出版历程

目录

通讯作者:
陈兆峰, E-mail: zhfchen@lzu.edu.cn