间充质干细胞在整形美容领域的应用

李竹君; 王晨羽; 龙笑

doi:10.12290/xhyxzz.2022-0036

间充质干细胞在整形美容领域的应用

doi: 10.12290/xhyxzz.2022-0036

李竹君^{1, 2},
王晨羽³,
龙笑^{1, 2, ,}

1.
中国医学科学院北京协和医院整形美容外科，北京 100730
2.
中国医学科学院北京协和医院疑难重症及罕见病国家重点实验室，北京 100730
3.
上海交通大学医学院附属第九人民医院整复外科，上海 200011

基金项目:

国家重点研发计划 2020YFE0201600

中国医学科学院医学与健康科技创新工程 2020-I2M-C & T-A-004

详细信息

通讯作者:
龙笑, E-mail：pumclongxiao@126.com

中图分类号: R622
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- 被引次数: 0
出版历程
- 收稿日期: 2022-01-24
- 录用日期: 2022-04-06
- 网络出版日期: 2022-04-19
- 刊出日期: 2022-05-30

Application of Mesenchymal Stem Cells in Plastic and Cosmetic Surgery

LI Zhujun^{1, 2},
WANG Chenyu³,
LONG Xiao^{1, 2
, ,}

1.
Department of Plastic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
2.
State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
3.
Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China

Funds:

National Key R & D Program of China 2020YFE0201600

CAMS Innovation Fund for Medical Sciences 2020-I2M-C & T-A-004

More Information

Corresponding author: LONG Xiao, E-mail: pumclongxiao@126.com

摘要

摘要: 间充质干细胞是具有自我更新和多向分化潜能的成体干细胞，存在于脂肪、骨髓和脐带等多种组织中，能通过直接分化或旁分泌的方式发挥修复组织缺损、促进血管生成、免疫调节、抗纤维化等多种作用。间充质干细胞在抗衰老、毛发/组织再生、创面愈合、抗纤维化等多个方面已有较为深入的研究，效果与安全性良好。未来仍需开展深入的基础研究以揭示其治疗机制，并进行长期的临床试验随访以考察其远期安全性。
- 间充质干细胞 /
- 整形手术 /
- 美容 /
- 组织再生
Abstract: Mesenchymal stem cells(MSCs) are adult stem cells that possess the ability of self-renewal and multi-lineage differentiation. They can be found in multiple tissue types, including adipose tissue, bone marrow and umbilical cord. MSCs can exert the effects of tissue repair, angiogenesis, immunoregulation, and anti-fibrosis through differentiation or paracrine function. Promising therapeutic effects of MSCs on skin aging, alopecia, tissue regeneration, wound healing, and anti-fibrosis have been observed. In general, MSCs exhibit favorable therapeutic effects and safety, but scrutinized research and clinical trials are still needed to reveal the mechanism of action as well as long-term efficacy and safety.
- mesenchymal stem cells /
- plastic surgery /
- cosmetic /
- tissue regeneration
注释:

作者贡献：李竹君负责查阅文献、撰写论文；王晨羽、龙笑负责论文构思及终稿审核、修订。

利益冲突：所有作者均声明不存在利益冲突

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参考文献(63)

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间充质干细胞在整形美容领域的应用

doi: 10.12290/xhyxzz.2022-0036

通讯作者:
龙笑, E-mail：pumclongxiao@126.com

计量

Application of Mesenchymal Stem Cells in Plastic and Cosmetic Surgery

Corresponding author: LONG Xiao, E-mail: pumclongxiao@126.com

计量

目录

留言板

间充质干细胞在整形美容领域的应用

doi: 10.12290/xhyxzz.2022-0036

通讯作者: 龙笑, E-mail：pumclongxiao@126.com

计量

出版历程

Application of Mesenchymal Stem Cells in Plastic and Cosmetic Surgery

Corresponding author: LONG Xiao, E-mail: pumclongxiao@126.com

计量

出版历程

目录

通讯作者:
龙笑, E-mail：pumclongxiao@126.com